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Neurogastroenterology and Motility, 2022
Co‐occurring (overlapping) irritable bowel syndrome (IBS), functional dyspepsia (FD), and heartburn has been observed. However, whether it is a distinct entity has not been established, nor what clinical, demographic, lifestyle, and psychological traits ...
Michael P. Jones +5 more
semanticscholar +1 more source
Co‐occurring (overlapping) irritable bowel syndrome (IBS), functional dyspepsia (FD), and heartburn has been observed. However, whether it is a distinct entity has not been established, nor what clinical, demographic, lifestyle, and psychological traits ...
Michael P. Jones +5 more
semanticscholar +1 more source
American Journal of Gastroenterology, 2016
To the Editor: We read with interest the clinical and systematic review on diagnosis and management of functional heartburn by Christine Hachem and Nicholas J. Shaheen (1). Authors have done a remarkable job that help readers to enter patients in correct categories of disease, despite the confusing nature of the topic.
SCARINGI, STEFANO +2 more
openaire +3 more sources
To the Editor: We read with interest the clinical and systematic review on diagnosis and management of functional heartburn by Christine Hachem and Nicholas J. Shaheen (1). Authors have done a remarkable job that help readers to enter patients in correct categories of disease, despite the confusing nature of the topic.
SCARINGI, STEFANO +2 more
openaire +3 more sources
Gastroesophageal reflux disease-related and functional heartburn: pathophysiology and treatment
Current Opinion in Gastroenterology, 2016Patients who continue to experience heartburn symptoms despite adequate-dose proton pump inhibitor therapy have unmet clinical needs. In this review, we focus on the most recent findings related to the mechanism of heartburn symptom generation, and on the treatment of gastroesophageal reflux disease-related and functional heartburn.The immunological ...
H. Miwa, T. Kondo, T. Oshima
semanticscholar +3 more sources
Neurogastroenterology and Motility, 2019
Mucosal innervation in non‐erosive reflux disease (NERD; pathological esophageal acid exposure, normal macroscopic mucosa) is clearly distinct from that of healthy volunteers (HV) and from patients with esophagitis or Barrett's esophagus: The nerves in ...
K. Nikaki +6 more
semanticscholar +1 more source
Mucosal innervation in non‐erosive reflux disease (NERD; pathological esophageal acid exposure, normal macroscopic mucosa) is clearly distinct from that of healthy volunteers (HV) and from patients with esophagitis or Barrett's esophagus: The nerves in ...
K. Nikaki +6 more
semanticscholar +1 more source
Are functional heartburn and functional dyspepsia one disorder?
Nature Reviews Gastroenterology & Hepatology, 2010The characteristics of functional heartburn remain poorly understood. Savarino et al. have now demonstrated that functional heartburn has more in common with functional dyspepsia than with nonerosive reflux disease. This study suggests that there is substantial overlap between functional heartburn and functional dyspepsia, and possibly that these two ...
Tiberiu Hershcovici, Ronnie Fass
openaire +1 more source
Visceral sensitivity in functional heartburn is not organ specific
The American Journal of Gastroenterology, 2003Purpose: Nomenclature and diagnostic criteria of functional GI disorders have become organ specific. Stratification by organ system may limit research and treatment algorithms and appears to be an inappropriate paradigm when the complex symptoms associated with functional disorders are catalogued.
Sheila Rodriguez-Stanley +3 more
openaire +2 more sources
American Journal of Gastroenterology, 2011
Refractory heartburn despite acid suppression may be explained by ongoing gastroesophageal reflux disease (GERD) or functional heartburn (FH), i.e., symptoms without evidence of GERD. Impedance-pH monitoring (impedance-pH) detects acid and nonacid reflux and is useful for evaluating acid-suppressed, refractory patients.
Marcelo F, Vela +4 more
openaire +2 more sources
Refractory heartburn despite acid suppression may be explained by ongoing gastroesophageal reflux disease (GERD) or functional heartburn (FH), i.e., symptoms without evidence of GERD. Impedance-pH monitoring (impedance-pH) detects acid and nonacid reflux and is useful for evaluating acid-suppressed, refractory patients.
Marcelo F, Vela +4 more
openaire +2 more sources
Digestion, 2018
Background: Combined 24-h intraesophageal pH-multichannel intraluminal impedance (24MII-pH) used for assessing gastroesophageal reflux disease by measuring baseline impedance (BI) requires a 24-h measuring period.
T. Yoshimine +9 more
semanticscholar +1 more source
Background: Combined 24-h intraesophageal pH-multichannel intraluminal impedance (24MII-pH) used for assessing gastroesophageal reflux disease by measuring baseline impedance (BI) requires a 24-h measuring period.
T. Yoshimine +9 more
semanticscholar +1 more source
Functional Heartburn: What It Is and How to Treat It
Gastrointestinal Endoscopy Clinics of North America, 2009Functional heartburn is considered one of the most common functional esophageal disorders. The disorder is more common in young women and is associated with other functional bowel disorders and psychological co-morbidity, primarily somatization. The etiology of functional heartburn remains unknown.
openaire +2 more sources
Established and Emerging Treatment Options for Functional Heartburn and Chest Pain
Current Treatment Options in Gastroenterology, 2016Functional heartburn and functional chest pain of presumed esophageal origin are characterized by symptoms suggesting an esophageal origin, but negative work-up on routine investigations, including ruling out gastroesophageal reflux disease. Visceral hypersensitivity is a potentially unifying pathophysiological concept, thought to underlie these ...
J. Tack, T. Vanuytsel, A. Pauwels
semanticscholar +3 more sources