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Comparison of Rectal and Esophageal Sensitivity in Women With Functional Heartburn
Gastroenterology Nursing, 2016This study tested the primary hypothesis that there is a correlation of maximum pain threshold (MPT) in the esophagus and rectum in persons with functional heartburn. Secondary aims evaluated correlations with initial perception threshold (IPT) and pain threshold (PT). This study explored objective sensory endpoints of IPT, PT, and MPT in the esophagus
Margaret, Freede +6 more
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Functional chest pain responds to biofeedback treatment but functional heartburn does not
European Journal of Gastroenterology & Hepatology, 2012Patients with functional esophageal disorders represent a challenging treatment group. The purpose of this study was to evaluate the role of biofeedback in the treatment of patients with functional esophageal disorders.In this prospective study, patients with typical/atypical symptoms of gastroesophageal reflux disease underwent upper endoscopy and 24 ...
Michael, Shapiro +5 more
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Light microscopy is useful to better define NERD and functional heartburn
Gut, 2013We read with great interest the well done pathophysiological study by Woodland et al 1 showing that an impaired oesophageal mucosal integrity, expressed by low baseline impedance values, is likely due to repeated acid reflux episodes, which contribute also to slow recovery after this challenge.
Savarino E +4 more
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Su1206: ASSOCIATION OF FUNCTIONAL HEARTBURN WITH ESOPHGEAL MORPHOLOGICAL ALTERNATION
Gastroenterology, 2022G. Song +6 more
semanticscholar +1 more source
Current Medical Research and Opinion, 2008
While functional heartburn (FH) and functional dyspepsia (FD) are recognized clinical entities, symptoms often overlap across both disorders. Despite their frequency, little is known of the underlying pathophysiology of overlapping symptoms. This study evaluated the effect of the 5-HT(4) agonist, tegaserod, on visceral sensitivity and symptom ...
Philip B, Miner +4 more
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While functional heartburn (FH) and functional dyspepsia (FD) are recognized clinical entities, symptoms often overlap across both disorders. Despite their frequency, little is known of the underlying pathophysiology of overlapping symptoms. This study evaluated the effect of the 5-HT(4) agonist, tegaserod, on visceral sensitivity and symptom ...
Philip B, Miner +4 more
openaire +2 more sources
Nonerosive reflux disease and functional heartburn are clearly separate entities
European Journal of Gastroenterology & Hepatology, 2013To The Editor: We read with interest the paper by Blaga et al on the clinical and functional profiles of patients with functional heartburn (FH) (1). The Authors must be congratulated because this is one of the first studies in which the population of FH is clearly separated from the other subgroups of NERD on the basis of an objective method (i.e ...
SAVARINO, EDOARDO VINCENZO +3 more
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Update on Functional Heartburn.
Gastroenterology & hepatologyThe definition of functional heartburn has been refined over the years. It is currently described, based upon Rome IV criteria, as typical heartburn symptoms in the presence of normal upper endoscopy findings (including normal biopsies), normal esophageal pH testing, and a negative association between symptoms and reflux events. Functional heartburn is
Takahisa, Yamasaki +2 more
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[Functional heartburn--update 2013].
MMW Fortschritte der Medizin, 2014Functional heartburn is a frequent disease which should be considered when heartburn does not respond to proton pump inhibitor (PPI) treatment. Functional heartburn is defined in the Rome-III-criteria. Differential diagnoses like gastroesophageal reflux disease (GERD), non erosive reflux disease (NERD) and hypertensive esophagus are diagnosed employing
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