Results 71 to 80 of about 15,605 (226)

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

Nonerosive reflux disease :comparative analysis of symptoms severity, endoscopic and 24-hours ph-impedance [PDF]

open access: yes, 2015
Background : Non--‐erosive reflux disease (NERD) has emerged as a real entity in the spectrum of gastroesophageal reflux disease (GERD) and may, indeed, represent the most common manifestation of reflux disease.
Nordin, Noorlina
core  

Morphology of the Esophageal Hiatus: Is It Different in 3 Types of Hiatus Hernias? [PDF]

open access: yes, 2020
Background/aimsThe esophageal hiatus is formed by the right crus of the diaphragm in the majority of subjects. Contraction of the hiatus exerts a sphincter-like action on the lower esophageal sphincter (LES). The aim is to study the hiatal anatomy (using
Ghahremani, Gary   +5 more
core   +1 more source

Changes in prevalence, incidence and spontaneous loss of gastro-oesophagealreflux symptoms : a prospective population-based cohort study, the HUNT study [PDF]

open access: yes, 2016
OBJECTIVE: Changes in the occurrence of gastro-oesophageal reflux symptoms (GORS) in the population remain uncertain. This study aimed to determine the prevalence changes, the incidence and the spontaneous loss of GORS.
Hveem, Kristian   +3 more
core   +1 more source

Clinical Characteristics and Outcomes of Incomplete Cardia Reconstruction Cases Following Multiple Anti‐reflux Mucosectomy/Anti‐reflux Mucosal Ablation Treatments

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Introduction Anti‐reflux mucosectomy (ARMS) and anti‐reflux mucosal ablation (ARMA) are novel endoscopic treatments for proton pump inhibitor or potassium‐competitive acid blocker‐refractory gastroesophageal reflux disease. These procedures induce scarring of the artificial ulcer at the gastric cardia, which tightens the enlarged cardiac ...
Ippei Tanaka   +8 more
wiley   +1 more source

Laryngopharyngeal reflux symptoms index: relation with the main symptoms of gastroesophageal reflux, voice usage level and voice screening [PDF]

open access: yes, 2012
PURPOSE: to determine the relation between Laryngopharyngeal Reflux Symptoms Index (LPRSI) and the main symptoms of gastroesophageal reflux disease (GERD) - heartburn and retroesternal pain - voice usage level and voice screening.
Behlau, Mara, Zucato, Barbara
core   +2 more sources

Utility of the Endoscopic Pressure Study Integrated System in Identifying Silent Gastroesophageal Reflux Disease During Routine Health Check‐ups

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives The endoscopic pressure study integrated system (EPSIS) is a novel functional endoscopic modality that records intragastric pressure (IGP) waveforms during CO2 insufflation to evaluate lower esophageal sphincter (LES) function and diagnose gastroesophageal reflux disease (GERD).
Yohei Nishikawa   +12 more
wiley   +1 more source

Functional heartburn: An underrecognized cause of PPI-refractory symptoms

open access: yesCleveland Clinic Journal of Medicine, 2019
Functional heartburn--persistent symptoms of esophageal reflux with no objective evidence of gastroesophageal reflux disease (GERD)--is the most common cause of failure of proton pump inhibitor (PPI) therapy, but it is often overlooked by internists and gastroenterologists.
Scott, Gabbard, Sonya, Vijayvargiya
openaire   +2 more sources

Is Single‐Session Peroral Endoscopic Myotomy With Fundoplication Safe and Effective in Achalasia? A Systematic Review and Meta‐Analysis

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
This meta‐analysis of nine studies (202 patients) demonstrates that peroral endoscopic myotomy with fundoplication (POEM‐F) achieves a technical success of 94.8% and significant symptom improvement (Eckardt score reduction from 8.3 to 1.1). Post‐procedural esophagitis occurred in 20.7% and wrap integrity was preserved in 75.7% on follow‐up, supporting ...
Yusuf Kagzi   +2 more
wiley   +1 more source

Epidemiology of functional gastrointestinal disorders using ROME III adult questionnaire, a population based cross sectional study in Karachi-Pakistan.

open access: yesPLoS ONE, 2022
ObjectiveFunctional Gastrointestinal Disorder (FGIDs) are a heterogenous group of disorders, with Irritable Bowel Syndrome (IBS) and Functional Dyspepsia (FD) being the most common disorders worldwide.
Shahab Abid   +4 more
doaj   +1 more source

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