Results 71 to 80 of about 10,268,847 (308)

Cortical hierarchy disorganization in major depressive disorder and its association with suicidality

Frontiers in Psychiatry, 2023
ObjectivesTo explore the suicide risk-specific disruption of cortical hierarchy in major depressive disorder (MDD) patients with diverse suicide risks.MethodsNinety-two MDD patients with diverse suicide risks and 38 matched controls underwent resting ...
Lin Shiwei, Zhang Xiaojing, Zhang Yingli, Chen Shengli, Lin Xiaoshan, Xu Ziyun, Hou Gangqiang, Qiu Yingwei   +7 more
doaj   +1 more source

Mapping the principal gradient onto the corpus callosum

NeuroImage, 2020
Gradients capture some of the variance of the resting-state functional magnetic resonance imaging (rsfMRI) signal. Amongst these, the principal gradient depicts a functional processing hierarchy that spans from sensory-motor cortices to regions of the ...
Patrick Friedrich, Stephanie J. Forkel, Michel Thiebaut de Schotten   +2 more
doaj   +1 more source

KEGG BRITE functional-hierarchies tree.

, 2020
KEGG BRITE functional-hierarchies tree and bar-plots of the degree of each functional hierarchy node, i.e. the number of Pan-Cancer genes associated to each functional hierarchy.
José M. Jerez (8626176), Francisco J. Veredas (8626179), Leonardo Franco (2994096), Guillermo López-García (8626173)   +3 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Mesoscale hierarchical organization of primary somatosensory cortex captured by resting-state-fMRI in humans

NeuroImage, 2021
The primary somatosensory cortex (S1) plays a key role in the processing and integration of afferent somatosensory inputs along an anterior-to-posterior axis, contributing towards necessary human function.
Geoffrey N. Ngo, Koen V. Haak, Christian F. Beckmann, Ravi S. Menon   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Semantic scope restrictions in complex verb constructions in Dutch

Linguistics, 2022
This article addresses the question of how and why verbs combine in complex verb constructions in Dutch. We discuss introspective data reported in reference grammars and add evidence from corpus data to uncover the systematic ways in which Dutch verbs ...
Coussé Evie, Bouma Gerlof
doaj   +1 more source

The neural signatures of social hierarchy-related learning and interaction: A coordinate- and connectivity-based meta-analysis

NeuroImage, 2021
Numerous neuroimaging studies have investigated the neural mechanisms of two mutually independent yet closely related cognitive processes aiding humans to navigate complex societies: social hierarchy-related learning (SH-RL) and social hierarchy-related ...
Siying Li, Frank Krueger, Julia A. Camilleri, Simon B. Eickhoff, Chen Qu   +4 more
doaj   +1 more source

DOES HIERARCHY STILL MATTER?

, 2023
reservedThis thesis regards hierarchy and its role in organizations. It will be discussed both the advantages and drawbacks of adopting a hierarchical structure instead of a flat one.
MUNARO, NICOLA
core