Results 131 to 140 of about 68,679 (255)

Multimorbidity patterns and associations with functional limitations among an aging population in prison

, 2018
© 2018 Objectives: Co-occurring chronic diseases are associated with functional limitations, particularly for the aging population ≥50 years old. Aging offenders (individual who are imprisoned) tend to have greater prevalence of chronic, mental health ...
Madison L. Gates, Wonsuk Yoo, Yoo, Wonsuk, Walker, Veronica, Peace N. Jessa, Veronica Walker, Gates, Madison L., Vivian Dicks, Jessa, Peace N., Elizabeth G. Hunter, Dicks, Vivian, Hunter, Elizabeth G.   +11 more
core   +1 more source

Commentary: Editorial—Whole-body electromyostimulation: A training technology to improve health and performance in humans? volume II

Frontiers in Physiology, 2022
Túlio Medina Dutra Oliveira, Marcelo Resende Machado, Marco Antonio Cavalcanti Garcia, Carla Malaguti   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Device-based physical activity levels among Finnish adolescents with functional limitations

, 2018
Background Monitoring physical activity among young adolescents with disabilities is a top academic priority. People with disabilities are a diverse group with various abilities in different human functioning. Therefore, we used a novel approach through
Villberg, Jari, Pauliina Husu (785329), Kwok W. Ng (12591166), Vasankari, Tomi, Kokko, Sami, Jari Villberg (5512241), Ng, Kwok, Tommi Vasankari (220901), Rintala, Pauli, Pauli Rintala (357379), Ng, Kwok W., Vasankari, Tommi, Husu, Pauliina, Sami Kokko (5512238)   +13 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Functional limitations associated with housing environmental problems among community - living older people

, 2010
This paper describes the functional limitations due to normal aging that are associated with difficulties in older persons housing environments. Literature review from occupational therapy, medicine and human kinetics was used to study the evolution of ...
Carmo Fialho, J. (author), Costa Branco De Oliveira Pedro, J.A., Cachadinha, C. (author), Carmo Fialho, J., Costa Branco De Oliveira Pedro, J.A. (author), Cachadinha, C.   +5 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Functional limitations and firearm purchases among low-income U.S. military veterans

Injury Epidemiology
Objectives Functional limitations may be associated with firearm ownership among veterans by amplifying perceptions of vulnerability and the need for security, yet their role remains underexplored despite emerging research on health-related factors ...
Alexander Testa, Jack Tsai
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Understanding consumer needs and preferences in new product development: the case of functional food innovations [PDF]

As the majority of new products fail it is important to focus on the needs and preferences of the consumers in new product development. Consumers are increasingly recognised as important co-developers of innovations, often developing new functions for ...
Rogier Donders, Ellen H.M. Moors
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