Results 91 to 100 of about 900,963 (349)

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Functional magnetic resonance imaging in schizophrenia

Dialogues in Clinical Neuroscience, 2010
The integration of functional magnetic resonance imaging (fMRI) with cognitive and affective neuroscience paradigms enables examination of the brain systems underlying the behavioral deficits manifested in schizophrenia; there have been a remarkable increase in the number of studies that apply fMRI in neurobiological studies of this disease.
Raquel E. Gur, Ruben C. Gur
openaire   +3 more sources

Effect of Nonsteroidal Anti‐Inflammatory Drugs on Sacroiliac Joint Inflammation, as Seen on Magnetic Resonance Imaging, in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective Imaging evidence of active sacroiliitis is important for diagnosis, classification, and monitoring of axial spondyloarthritis (axSpA). However, there is no consistent guidance on whether patients should temporarily stop nonsteroidal anti‐inflammatory drugs (NSAIDs) before magnetic resonance imaging (MRI).
Gareth T. Jones, Alexander N. Bennett, Raj Sengupta, Pedro M. Machado, Helena Marzo‐Ortega, Lorna Aucott, Margaret A. Hall‐Craggs, Timothy J. P. Bray, Alan Bainbridge, Ruaridh M. Gollifer, Gary J. Macfarlane   +10 more
wiley   +1 more source

No difference in postprandial mesenteric blood flow between healthy younger and elderly individuals

Scientific Reports
We recently used phase-contrast magnetic resonance imaging (PC-MRI) to demonstrate an attenuated postprandial blood flow response in the superior mesenteric artery (SMA) in patients with Parkinson's disease compared to age- and sex-matched healthy ...
Thomas Hartwig Siebner, Jens Dahlgaard Hove, Christopher Fugl Madelung, Oliver James Hulme, Flemming Bendtsen, Hartwig Roman Siebner, Mads Barløse   +6 more
doaj   +1 more source

Knee crepitus and osteoarthritis features in young adults following traumatic knee injury

Arthritis Care &Research, Accepted Article.
Objective This study explored the association between knee crepitus and the presence, and worsening, of structural osteoarthritis features and self‐reported outcomes in young adults following traumatic knee injury. Methods One‐year following anterior cruciate ligament reconstruction (ACLR), 112 participants (41 female participants; median age 28 years)
Jamon L Couch, Brooke E Patterson, Kay M Crossley, Ali Guermazi, Matthew G King, Danilo De Oliveira Silva, Jackie L Whittaker, Michael A Girdwood, Adam G Culvenor   +8 more
wiley   +1 more source

The effect of foot orthoses on midfoot pain and the volume of bone marrow lesions in the midfoot: a randomized mechanism of action study

Arthritis Care &Research, Accepted Article.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain and MRI‐confirmed midfoot BMLs.
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

Correlations between cognitive reserve, gray matter, and cerebrospinal fluid volume in healthy elders and mild cognitive impairment patients

Frontiers in Neurology
ObjectiveTo explore the effect of cognitive reserve (CR) on brain volume and cerebrospinal fluid (CSF) in patients with mild cognitive impairment (MCI) and healthy elders (HE).Methods31 HE and 50 MCI patients were collected in this study to obtain ...
Liang Zhou, Liang Zhou, Liang Zhou, Wenxia Yang, Wenxia Yang, Wenxia Yang, Yang Liu, Yang Liu, Yang Liu, Jiachen Li, Jiachen Li, Jiachen Li, Mengmeng Zhao, Guangyao Liu, Guangyao Liu, Jing Zhang, Jing Zhang   +16 more
doaj   +1 more source

Cerebellar activation associated with model-based estimation of tool-use consequences

Behavioral and Brain Functions, 2019
Background Dexterous tool use is considered to be underpinned by model-based control relying on acquired internal models of tools. In particular, this is the case in situations where available sensory feedback regarding the consequences of tool use is ...
Sayako Ueda, Hiroyuki Sakai, Kenichi Ueno, Kang Cheng, Takatsune Kumada   +4 more
doaj   +1 more source

Functional magnetic resonance imaging of human prefrontal cortex activation during a spatial working memory task. [PDF]

, 1994
Gregory McCarthy, Andrew M. Blamire, Aina Puce, Anna C. Nobre, G Bloch, Fahmeed Hyder, P. Goldman-Rakic, Robert G. Shulman   +7 more
openalex   +1 more source