Results 131 to 140 of about 229,155 (322)

Regional-based static and dynamic alterations in Alzheimer disease: a longitudinal study

open access: yesArquivos de Neuro-Psiquiatria
Background Alzheimer disease (AD) leads to cognitive decline and alters functional connectivity (FC) in key brain regions. Resting-state functional magnetic resonance imaging (rs-fMRI) assesses these changes using static-FC for overall ...
Kuppe Channappa Usha   +2 more
doaj   +1 more source

Task-Evoked Functional Activation and Coupling With CSF Flow Detected in the Human Brain With Ultrashort Echo Time fMRI at 7 T. [PDF]

open access: yesNMR Biomed
Ultrashort and zero echo time (UTE and ZTE) MRI techniques generate functional contrast through inflow effects, making them suitable for studying cerebral blood flow and cerebrospinal fluid (CSF) dynamics. In a 7‐T study of 13 participants performing a visual task, we demonstrate that UTE produced robust, reproducible activations with group‐level ...
Ponticorvo S   +7 more
europepmc   +2 more sources

Investigating human audio-visual object perception with a combination of hypothesis-generating and hypothesis-testing fMRI analysis tools [PDF]

open access: yes, 2011
Primate multisensory object perception involves distributed brain regions. To investigate the network character of these regions of the human brain, we applied data-driven group spatial independent component analysis (ICA) to a functional magnetic ...
van den Bosch, Jasper J F   +27 more
core   +1 more source

Brain reward function in young people with cannabis use disorder: A functional magnetic resonance imaging study

open access: yesAddiction, EarlyView.
Abstract Background and Aims Cannabis use disorder (CUD) affects ~50 million people globally. Neuroscientific theories suggest that a blunted neural response to non‐drug rewards is a hallmark of substance use disorders; however, this remains untested in CUD. The current study tested whether brain reward system responses to the anticipation and feedback
Martine Skumlien   +15 more
wiley   +1 more source

Phase coupling between eye and brain pulsations is bidirectional and modulated by the parasympathetic system – An fMREye study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Physiological pulsations driven by cardiac, respiratory, and vasomotor activity are essential for solute transport within perivascular and perineural cerebrospinal fluid (CSF) pathways that support brain and eye clearance systems. Previous studies have shown that parasympathetic blockade significantly reduces ocular pulsation power and
Ebrahimi Seyed‐Mohsen   +9 more
wiley   +1 more source

Advances of Studies on the Underlying Mechanism of Acupuncture Efficacies by Using Functional Magnetic Resonance Imaging

open access: yes针刺研究, 2009
In the present paper the authors review recent progress in the study on the underlying mechanism of acupuncture effects by using functional magnetic resonance imaging(fMRI) from 1) fMRI imaging technology,2) the meridian-collateral system of Chinese ...
REN Xiu-jun, WANG Bao-guo1
doaj  

Safety pharmacology of acute mescaline administration in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber   +4 more
wiley   +1 more source

Rest-fMRI—A Potential Substitute for Task-fMRI?

open access: yesIndian Journal of Radiology and Imaging
Objective The aim of this study was to assess the reliability of resting-state functional magnetic resonance imaging (rest-fMRI) in mapping language areas for preoperative planning, versus standard task-based techniques, which are at times ...
Santosh S. Gupta   +2 more
doaj   +1 more source

Neuroanatomical and neurofunctional brain basis of cognitive deficits in adolescent subjects who were born preterm. Structural and functional magnetic resonance study [PDF]

open access: yes, 2006
[eng] The general aim of this thesis is to study the cerebral basis of cognitive disturbances in adolescents with history of premature birth (PB). As previous manual volumetric investigations in PB samples, we quantitatively demonstrated the presence of ...
Giménez Navarro, Mónica
core  

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

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