Results 131 to 140 of about 6,198,061 (298)

Modified TPP-MoS₂ QD Blend as a Bio-Functional Model for Normalizing Microglial Dysfunction in Alzheimer's Disease. [PDF]

Neurol Int, 2023
Alomari OA, Qusti S, Balgoon M, Aljoud F, Alamry KA, Hussein MA.   +5 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

DEVELOPMENT OF A GENERALIZED FUNCTIONAL MODEL OF THE DUAL MAINTENANCE OF VOCATIONAL TRAINING OF FUTURE ENGINEERS-TEACHERS OF A COMPUTER PROFILE

Ìнформаційні технології в освіті, 2015
The approaches are analyzed and the development of a generalized functional model of the dual content of training of future engineers-teachers of computer type is implemented in the article.
V. Khomenko
doaj  

Research of efficiency of introduction structural functional case of the system of physical preparation of servicemen of service safety of Ukraine frame [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
The factors of increase of specialist's level of professional administrative jurisdiction are considered to operatively-battle and to physical preparation.
Konovalov V.V.
doaj  

Rethinking the framework constructed by counterfactual functional model. [PDF]

Appl Intell (Dordr), 2022
Wang C, Liu L, Sun S, Wang W.
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

A functional model for studying common trends across trial time in eye tracking experiments. [PDF]

Stat Biosci, 2023
Dong M, Telesca D, Sugar C, Shic F, Naples A, Johnson SP, Li B, Atyabi A, Xie M, Webb SJ, Jeste S, Faja S, Levin AR, Dawson G, McPartland JC, Şentürk D, Autism Biomarkers Consortium for Clinical Trials.   +16 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A functional model of adult dentate gyrus neurogenesis. [PDF]

Elife, 2021
Gozel O, Gerstner W.
europepmc   +1 more source