Results 111 to 120 of about 6,198,061 (298)
Functional-Structural Modelling of Gramineae
, 2007 The Gramineae have been a pioneer group among non-woody plants to be modelled with the approach of functional-structural plant modelling (FSPM). During the past decade, models have focussed on morphological aspects of plant development. They now provide crop scientists with general guidelines for building new cereal models. We present some of them here,
Fournier, Christian +6 more
openaire +4 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Concept of an integrated mobile application aiding electromobility
Transport, 2019 Increasing acceptance of electromobility is an important step towards sustainable transportation. However, besides its obvious environmental and economic benefits, the technology of Electric Vehicles (EVs) still has some significant operational drawbacks
Csaba Csiszár, Gábor Pauer
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Electronic Journal of Differential Equations, 2017 In this article we consider a second-order Sturm-Liouville operator with a spectral parameter in the boundary condition on bounded time scales. We construct a selfadjoint dilation of the dissipative Sturm-Liouville operators.
Bilender P. Allahverdiev +2 more
doaj
Theoretical and Mathematical Physics, 2001 The correlation functions are calculated for the two dimensional Ising model with free boundary conditions and the two dimensional Ising model with periodic boundary conditions.
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Pmf-cpi: assessing drug selectivity with a pretrained multi-functional model for compound-protein interactions. [PDF]
J Cheminform, 2023 Song N +5 more
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source