Results 51 to 60 of about 5,728,125 (229)

Subthalamic Nucleus Oscillatory Characteristics in Meige, Cervical Dystonia and Generalized Dystonia

Annals of Clinical and Translational Neurology
Objective Deep brain stimulation offers a unique opportunity to record neural activity of the basal ganglia. While much work in dystonia has focused on the globus pallidus internus, expanding research to investigate subthalamic nucleus (STN) activity in ...
Zhu Guan‐Yu, Yin Zi‐Xiao, Chen Ying‐Chuan, Timon Merk, Thomas Binns, Ma Ruo‐Yu, Du Ting‐Ting, Liu Yu‐Ye, Xie Hu‐Tao, Shi Lin, Yang An‐Chao, Meng Fan‐Gang, Wolf‐Julian Neumann, Andrea A. Kühn, Zhang Jian‐Guo   +14 more
doaj   +1 more source

Use of non-invasive neurostimulation for rehabilitation in functional movement disorders

Frontiers in Rehabilitation Sciences, 2022
Functional movement disorders (FMD) are a subtype of functional neurological disorders which involve abnormal movements and include multiple phenomenologies. There is a growing interest in the mechanism, diagnosis, and treatment of these disorders.
Talyta Grippe, Talyta Grippe, Talyta Grippe, Naaz Desai, Tarun Arora, Robert Chen, Robert Chen, Robert Chen   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Attention in Parkinson’s Disease Mimicking Suggestion in Psychogenic Movement Disorder [PDF]

, 2012
The various reported psychogenic movement disorders (PMDs) include tremor, dystonia, myoclonus, gait disorder, Parkinsonism, tics, and chorea. Although it is not easy to diagnose PMDs, several features such as distractibility, entrainment, suggestion and
Jong Sam Baik
core   +1 more source

Similarities and Differences in Functional Movement Disorders and Functional Seizures at a Tertiary Care Center: A Prospective Study

Annals of Indian Academy of Neurology
Background: Functional movement disorders (FMDs) and functional seizure (FS) are the two most important subcategories of functional neurologic disorders (FNDs).
Anumeha Mishra, Sanjay Pandey
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Challenges in the diagnosis of functional movement disorders in older adults in Latin America: A narrative review

Acta Neurológica Colombiana
Introduction: Functional movement disorders (FMDs) are abnormal involuntary movements that cannot be explained by structural neurological disease and fall under the spectrum of functional neurological disorders.
Maria Isabella Bonilla Arbeláez , Manasicha Wongpaiboon, Enrique Urrea Mendoza, Maria Juliana Urrea Perez, Adolfo Ramirez-Zamora   +4 more
doaj   +1 more source

Satisfaction and Occupational Performance in Patients with Functional Movement Disorder

Open Journal of Occupational Therapy, 2017
Background: Behavioral Shaping Therapy (BeST) is a program that uses a multidisciplinary approach to treat patients diagnosed with functional movement disorder (FMD).
Sarah E. Dahlhauser, Amanda Theuer
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source