Results 91 to 100 of about 742,922 (307)

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Changes of functional connectivity in the left frontoparietal network following aphasic stroke

Frontiers in Behavioral Neuroscience, 2014
Language is an essential higher cognitive function supported by large-scale brain networks. In this study, we investigated functional connectivity changes in the left frontoparietal network (LFPN), a language-cognition related brain network in aphasic ...
Dan eZhu, Ying eGao
doaj   +1 more source

Improvising at rest: Differentiating jazz and classical music training with resting state functional connectivity

NeuroImage, 2020
Jazz improvisation offers a model for creative cognition, as it involves the real-time creation of a novel, information-rich product. Previous research has shown that when musicians improvise, they recruit regions in the Default Mode Network (DMN) and ...
Alexander Belden, Tima Zeng, Emily Przysinda, Sheeba Arnold Anteraper, Susan Whitfield-Gabrieli, Psyche Loui   +5 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Widespread disruption of functional brain organization in early-onset Alzheimer's disease.

PLoS ONE, 2014
Early-onset Alzheimer's disease (AD) patients present a different clinical profile than late-onset AD patients. This can be partially explained by cortical atrophy, although brain organization might provide more insight.
Sofie M Adriaanse, Maja A A Binnewijzend, Rik Ossenkoppele, Betty M Tijms, Wiesje M van der Flier, Teddy Koene, Lieke L Smits, Alle Meije Wink, Philip Scheltens, Bart N M van Berckel, Frederik Barkhof   +10 more
doaj   +1 more source

Dynamic Reconfiguration of Visuomotor-Related Functional Connectivity Networks [PDF]

The Journal of Neuroscience, 2016
Cognitive functions arise from the coordination of large-scale brain networks. However, the principles governing interareal functional connectivity dynamics (FCD) remain elusive. Here, we tested the hypothesis that human executive functions arise from the dynamic interplay of multiple networks.
Brovelli, Andrea, Badier, Jean-Michel, Bonini, Francesca, Bartolomei, Fabrice, Coulon, Olivier, Auzias, Guillaume   +5 more
openaire   +3 more sources

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Distinct Aging Effects on Functional Networks in Good and Poor Cognitive Performers

Frontiers in Aging Neuroscience, 2016
Brain network hubs are susceptible to normal aging processes and disruptions of their functional connectivity are detrimental to decline in cognitive functions in older adults.
Annie Lee, Mingzhen Tan, Anqi Qiu
doaj   +1 more source

Mapping the functional and structural connectivity of the scene network

Human Brain Mapping
AbstractThe recognition and perception of places has been linked to a network of scene‐selective regions in the human brain. While previous studies have focussed on functional connectivity between scene‐selective regions themselves, less is known about their connectivity with other cortical and subcortical regions in the brain.
David M. Watson, Timothy J. Andrews
openaire   +3 more sources