Results 211 to 220 of about 4,561,300 (269)

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao   +7 more
wiley   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

open access: yesAdvanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang   +12 more
wiley   +1 more source

Functional neurological disorder: defying dualism

open access: yesWorld Psychiatry
Stone, Jon; id_orcid 0000-0001-9829-8092   +3 more
openaire   +3 more sources

Overcoming Artificial Structures in Resolution‐Enhanced Hi‐C Data by Signal Decomposition and Multi‐Scale Attention

open access: yesAdvanced Science, EarlyView.
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li   +6 more
wiley   +1 more source

Relationships between brain functional connectivity and resting cardiac autonomic profiles in functional neurological disorder: A pilot study. [PDF]

open access: yesNeuroimage Clin
Bleier C   +10 more
europepmc   +1 more source

Clinical and demographic associations of recorded feigning in functional neurological disorder. [PDF]

open access: yesBrain Commun
Berlot R   +6 more
europepmc   +1 more source

Ocular Motor Abnormalities in Functional Neurological Disorder: A Video-Oculography Study. [PDF]

open access: yesMov Disord Clin Pract
Sangare A   +13 more
europepmc   +1 more source

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