Results 1 to 10 of about 4,250,676 (289)

A functional observational battery for evaluation of neurological outcomes in a rat model of acute bacterial meningitis [PDF]

open access: yesIntensive Care Medicine Experimental, 2020
Background Acute bacterial meningitis is a disease with a high mortality and a high incidence of neurological sequelae in survivors. There is an acute need to develop new adjuvant therapies.
Jane Fisher   +6 more
doaj   +10 more sources

Vision evaluation by functional observational battery, operant behavior test, and light/dark box test in retinal dystrophic RCS rats versus normal rats [PDF]

open access: yesHeliyon, 2019
Background: Vision plays a key role in some behavior tests for rats. Okayama University-type retinal prosthesis (OUReP) is a photoelectric dye-coupled polyethylene film which generates electric potential in response to light and stimulates nearby neurons.
Toshihiko Matsuo   +7 more
doaj   +4 more sources

Advanced imaging–integrated rTMS therapy for frontal network recovery after traumatic brain injury [PDF]

open access: yesFrontiers in Human Neuroscience
BackgroundTraumatic brain injury is frequently followed by persistent executive dysfunction linked to disruption of frontal and frontoparietal networks.
Nan Hu   +4 more
doaj   +2 more sources

Alcoholic neuropathy associated with chronic alcohol intake

open access: yesIBRO Neuroscience Reports, 2022
Alcoholic neuropathy (AN), a debilitating condition that mainly affects chronic alcohol drinkers, is thought to cause lesions in the peripheral nervous system leading to sensory, autonomic, and motor dysfunctions.
Maria Eduarda Tessitore   +8 more
doaj   +1 more source

Validity and Reliability of the Short Physical Performance Battery Tool in Institutionalized Spanish Older Adults

open access: yesNursing Reports, 2023
Background: In order to be used safely, accurately and reliably, measuring instruments in the health field must first be validated, for which the study of their psychometric properties is necessary. The Short Physical Performance Battery (SPPB) tool is a
Mirian Santamaría-Peláez   +7 more
doaj   +1 more source

Preclinical in vivo Neurotoxicity Studies of Drug Candidates

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2020
Neurotoxic effects are one of the common reasons for discontinuation of preclinical and/or clinical studies. Preclinical evaluation of neurotoxic effects is complicated due to a wide range of manifestations and degrees of severity.
N. V. Eremina   +3 more
doaj   +1 more source

Addenbrooke's cognitive examination III: diagnostic utility for detecting mild cognitive impairment and dementia in Parkinson's disease

open access: yesArquivos de Neuro-Psiquiatria, 2023
Background Cognitive deficit in Parkinson disease (PD) is an important cause of functional disability in these patients and early detection, with sensitive instruments, can contribute to longitudinal monitoring.
Nariana Mattos Figueiredo Sousa   +1 more
doaj   +1 more source

Body composition and functional performance of older adults

open access: yesOsteoporosis and Sarcopenia, 2022
Objectives: To determine if anthropometric variables, body composition, medication and gender are associated with functional performance and to compare these variables between octogenarians with high and low functional performance. Methods: Observational,
Diane Nogueira Paranhos Amorim   +4 more
doaj   +1 more source

Cognitive status in chronic kidney disease elderly patients. [PDF]

open access: yesThe Egyptian Journal of Geriatrics and Gerontology, 2023
Background: Chronic Kidney disease (CKD) in elderly patients leads to dementia and cognitive impairment which leads to functional dependence and recurrent hospitalization.Objective: To assess different cognitive domains in CKD elderly patients.Methods: A
Yumna Elgazzar   +3 more
doaj   +1 more source

The Evaluation of the Potency of Newly Developed Oximes (K727, K733) and Trimedoxime to Counteract Acute Neurotoxic Effects of Tabun in Rats

open access: yesActa Medica, 2016
Aim: The ability of two newly developed oximes (K727, K733) to reduce tabun-induced acute neurotoxic signs and symptoms was evaluated and compared with currently available trimedoxime in rats.
Jiří Kassa   +2 more
doaj   +1 more source

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