Results 181 to 190 of about 1,160,625 (318)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Predicting post-stroke functional outcome using explainable machine learning and integrated data. [PDF]

Sci Rep
Olsson J, Stanne TM, Andersson B, Jern C.   +3 more
europepmc   +1 more source

A Case-Control Comparison of Surgical and Functional Outcomes of Robotic-Assisted Spleen-Preserving Left Side Pancreatectomy versus Pure Laparoscopy [PDF]

, 2016
Luca Morelli, Simone Guadagni, Matteo Palmeri, Gregorio Di Franco, Giovanni Caprili, C D’Isidoro, Luca Bastiani, Giulio Di Candio, Andrea Pietrabissa, Franco Mosca   +9 more
openalex  

Long-term outcomes of functional surgery for attic cholesteatoma

, 2016
Erdem Atalay Çetinkaya, İbrahim Çukurova, Levent Olgun, Raci Kabakçı   +3 more
openalex   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A Functional Outcome on Different Surgical Treatment Modalities of Bimalleolar Fractures in Adults. [PDF]

Cureus
S G, Kandhasamy V, C S V, Baskar S N, M S.   +4 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Early surrogates of functional outcome after thrombectomy for MCA-M2 occlusions. [PDF]

Sci Rep
Kniep HC, Meyer L, Broocks G, Bechstein M, Heitkamp C, Winkelmeier L, Faizy T, Feyen L, Brekenfeld C, Flottmann F, Schell M, Hanning U, Thomalla G, Fiehler J, Gellißen S, German Stroke Registry-Endovascular Treatment (GSR-ET).   +15 more
europepmc   +1 more source

FUNCTIONAL OUTCOME OF PLATING IN PROXIMAL TIBIA FRACTURES USING MINIMALLY INVASIVE PERCUTANEOUS PLATE OSTEOSYNTHESIS

, 2017
Pradeep Kumar Verma, Prateek Ahlawat, Hari Babu Meena, Kumar Rohit, P K Lakhtakia   +4 more
openalex   +1 more source