Results 201 to 210 of about 1,160,625 (318)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Short-term functional outcome and pain assessment after spinal decompression for spondylodiscitis. [PDF]

J Med Life
Șendrea B, Voicu BG, Valeanu SM, Tudorache A, Stanciu MG, Cergan R.   +5 more
europepmc   +1 more source

Correlation Between the Insall-Salvati Ratio and Functional Outcomes After Total Knee Arthroplasty [PDF]

Amandeep S Bakshi, Davinder Singh, Jaspreet Singh, Sudhanshu Arya, MUKUL SHARMA   +4 more
openalex   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Functional Outcome After Surgery for Popliteal Artery Entrapment Syndrome. [PDF]

EJVES Vasc Forum
Treil L, Kuntz S, Chakfe N, Lejay A.
europepmc   +1 more source

Table 1_Increased triglyceride-glucose index is associated with adverse functional outcome for patients with aneurysmal subarachnoid hemorrhage after surgical clipping and endovascular coiling: insights from a large cohort study.docx

Xielin Tang (22225945), Bingcheng Zhu (4886260), Minghao Liu (3431642), Fa Lin (12237419), Runting Li (3723301), Wenxiong Song (8812241), Jionghao Xue (20594426), Liangxue Zhou (5518397), Xiaolin Chen (453167)   +8 more
openalex   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Circulating Short-Chain Fatty Acid Profile Predicts Functional Outcome After Moderate-to-Severe Traumatic Brain Injury. [PDF]

Crit Care Explor
Lieberman OJ, Nittala S, Rojas-Valencia L, Baranzini SE, Singhal NS, Hemphill JC, Amorim E, Ferguson AR, Hinson HE.   +8 more
europepmc   +1 more source

Reduction in programmed cell death and improvement in functional outcome of transient focal cerebral ischemia after administration of granulocyte-macrophage colony-stimulating factor in rats

, 2009
TaeHo Kong, Jung-Kyoung Choi, Hyeonseon Park, Byung Hyune Choi, Brian Snyder, Shefqat Bukhari, Na-Kyeong Kim, Xian Huang, So Ra Park, Hyung Chun Park, Yoon Ha   +10 more
openalex   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source