Results 51 to 60 of about 1,548,583 (268)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Properties of d’Alembert functions

Aequationes mathematicae, 2009
We study properties of solutions f of d’Alembert’s functional equations on a topological group G. For nilpotent groups and for connected, solvable Lie groups G, we prove that f has the form \(f(x) = (\gamma(x)+\gamma(x^{-1}))/2, x \in G\), where γ is a continuous homomorphism of G into the multiplicative group \({\mathbb{C}} \setminus \{0\}\).
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Doubling properties of caloric functions

Applicable Analysis, 2006
We prove local quantitative estimates of unique continuation for solutions to parabolic equations: doubling properties and two-sphere one-cylinder inequalities.
L. ESCAURIAZA, F. J. FERNANDEZ, VESSELLA, SERGIO   +2 more
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Testing Properties of Generic Functions [PDF]

, 2007
A datatype-generic function is a family of functions indexed by (the structure of) a type. Examples include equality tests, maps and pretty printers. Property based testing tools like QuickCheck and Gast support the definition of properties and test-data generators, and they check if a monomorphic property is satisfied by the test cases.
Patrik Jansson, Johan Jeuring, Laurence Cabenda, Gerbo Engels, Jacob Kleerekoper, Sander Mak, Michiel Overeem, Kees Visser   +7 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Comparative study of the structural and functional properties of protein isolates prepared from edible vegetable leaves

International Journal of Food Properties, 2020
Isoelectric precipitation was used to produce protein isolates (>90% protein contents) from three edible vegetable leaves. Amaranth (ALI), eggplant (ELI) and fluted pumpkin (FLI) leaf protein were isolated to study their conformational structures ...
Akinsola A. Famuwagun, Adeola M. Alashi, Saka O. Gbadamosi, Kehinde A. Taiwo, Durodoluwa J. Oyedele, Odunayo C. Adebooye, Rotimi E. Aluko   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A seed-extended algorithm for detecting protein complexes based on density and modularity with topological structure and GO annotations

BMC Genomics, 2019
Background The detection of protein complexes is of great significance for researching mechanisms underlying complex diseases and developing new drugs. Thus, various computational algorithms have been proposed for protein complex detection. However, most
Rongquan Wang, Caixia Wang, Liyan Sun, Guixia Liu   +3 more
doaj   +1 more source