Results 101 to 110 of about 566,644 (262)

An Intelligent Model to Predict Functional and Non-Functional Requirements From Software Requirements Specification

IEEE Access
Automated classification of Functional Requirements (FRs) and Non-Functional Requirements (NFRs) is a fundamental task in requirements engineering, yet it remains challenging due to the short length, domain specificity, and severe class imbalance of ...
Martina Girgis Said, Laila M. El-Fangary, Safaa M. Azzam, Amr A. Abohany   +3 more
doaj   +1 more source

Functional Requirements for Medical Data Integration into Knowledge Management Environments: Requirements Elicitation Approach Based on Systematic Literature Analysis. [PDF]

J Med Internet Res, 2023
Kinast B, Ulrich H, Bergh B, Schreiweis B.   +3 more
europepmc   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Classification of Non-Functional Requirements From IoT Oriented Healthcare Requirement Document. [PDF]

Front Public Health, 2022
Khurshid I, Imtiaz S, Boulila W, Khan Z, Abbasi A, Javed AR, Jalil Z.   +6 more
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

iNKT subsets differ in their developmental and functional requirements on Foxo1. [PDF]

Proc Natl Acad Sci U S A, 2021
Zhang H, Zhang Y, Pan J, Wu Q, Huang Y, Bai S, Tian C, Zhu M, Lian Z, Li F, Tian Z, Bai L.   +11 more
europepmc   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Characteristics of cohort data management systems (CDMS): a scoping review

BMC Medical Research Methodology
Cohort studies are a core aspect of clinical research which helps to gather a large volume of data over time. As digital technologies evolve, managing these data has become increasingly complex. Therefore, the use of cohort data management systems (CDMS)
Arezoo Abasi, Haleh Ayatollahi, Seyed Abbas Motevalian   +2 more
doaj   +1 more source

On systematically building a controlled natural language for functional requirements. [PDF]

Empir Softw Eng, 2021
Veizaga A, Alferez M, Torre D, Sabetzadeh M, Briand L.   +4 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source