Results 81 to 90 of about 566,644 (262)

The Function of Normative Process-Requirements

open access: yesDialectica, 2012
This paper discusses whether rationality, morality or prudence impose process-requirements upon us. It has been argued that process-requirements fulfil two essential functions within a system of rational, moral or prudential requirements. These functions are considered to prove the existence of process-requirements.
openaire   +2 more sources

Design of the data-driven software application for identification, population monitoring, and risk assessment for lions in Serengeti Tanzania [PDF]

open access: yesComputational Ecology and Software
This study presents a design of a Data-Driven software application for identification, population monitoring, and risk assessment for lions in Serengeti Tanzania.
Ambokile Okey   +2 more
doaj  

Cross-Project Multiclass Classification of EARS-Based Functional Requirements Utilizing Natural Language Processing, Machine Learning, and Deep Learning

open access: yesSystems
Software requirements are primarily classified into functional and non-functional requirements. While research has explored automated multiclass classification of non-functional requirements, functional requirements remain largely unexplored.
Touseef Tahir   +3 more
doaj   +1 more source

An Ontology for Specifying and Tracing Requirements Engineering Artifacts and Test Artifacts

open access: yesCLEI Electronic Journal, 2019
This paper proposes an ontology that defines and integrates the concepts adopted for use cases and test cases specification. These concepts belong to the metamodels of different Requirements Engineering and testing management supporting tools, and their ...
María Luciana Roldán   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Functional requirements decomposition in set-based design

open access: yesDesign Science
Designing systems is typically uncertain and ambiguous at the early stages. Set-based design (SBD) supports alternative exploration and gradual uncertainty reduction during the early lifecycle, making it practical for complex system design.
Minghui Sun   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Engineering Functional Requirements

open access: yes
Requirements Engineering (RE) is a critical sub-field of engineering that deals with identifying, analysing, specifying, modelling, and validating the user needs and constraints for a system. This not only holds for Software Engineering (SE) but for engineering in general (e.g., for building bridges and other artefacts as well).
openaire   +1 more source

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