Results 71 to 80 of about 566,644 (262)
ARE MITOTIC FUNCTIONS REQUIRED IN MEIOSIS? [PDF]
Genetics, 1974 ABSTRACT Sporulation of diploid yeasts (Saccharomyces cerevisiae), homozygous or heterozygous for temperature-sensitive mitotic cell-cycle mutations, was examined at the restrictive and permissive temperatures. Twenty genes, represented by 32 heterozygotes and 60 homozygotes, were divided into three groups, showing (i) normal sporulation,
openaire +2 more sources
Functional requirements for bibliographic records (FRBR)
Cybrarians Journal, 2005 The study deals with the definition of one of the modern standards used in the field of indexing, called the functional requirements for the bibliographic record FRBR.
Amal Abdelqader
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A Conceptual Model of an Oncology Information System
Cancer Management and Research, 2020 Azadeh Yazdanian,1 Haleh Ayatollahi,2,3 Azin Nahvijou4 1Department of Medical Records and Health Information Technology, School of Allied Medical Sciences, Mazandaran University of Medical Sciences, Sari, Iran; 2Health Management and Economics Research ...
Yazdanian A, Ayatollahi H, Nahvijou A
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Functional requirements for measuring driver state/competence and vehicle status in selected use ...
Colin Eddie +3 more
openaire +3 more sources
机车电传动, 2020 The full automatic operation system of urban rail transport was introduced and the full automatic operation scenes were untangled. Taking the automatic car wash scene and the large passenger flow operation scene as examples for analysis, the functional ...
Pengzhe WEN +3 more
doaj
Determining Interdependencies among NFRs in Agile Environment to Reduce Conflicts
EAI Endorsed Transactions on Mobile Communications and Applications, 2018 NFRs play a very key role in the development of high quality software. As NFRs are quality attributes of the software system, so it must be dealt properly and with care in the early phases of software development otherwise it will lead the system to ...
Jawad Ali +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source