Results 71 to 80 of about 5,666,463 (234)

Analysis on Full Automatic Operation Scenes and Related Functional Requirements of Urban Railway Transport

open access: yes机车电传动, 2020
The full automatic operation system of urban rail transport was introduced and the full automatic operation scenes were untangled. Taking the automatic car wash scene and the large passenger flow operation scene as examples for analysis, the functional ...
Pengzhe WEN   +3 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Functional Requirements for Bibliographic Records: Final Report

open access: yes, 2013
The purpose of this study is to delineate in clearly defined terms the functions performed by the bibliographic record with respect to various media, various applications, and various user needs.
IFLA Study Group on the Functional Requirements for Bibliographic Records
core   +3 more sources

Cross-Project Multiclass Classification of EARS-Based Functional Requirements Utilizing Natural Language Processing, Machine Learning, and Deep Learning

open access: yesSystems
Software requirements are primarily classified into functional and non-functional requirements. While research has explored automated multiclass classification of non-functional requirements, functional requirements remain largely unexplored.
Touseef Tahir   +3 more
doaj   +1 more source

An Ontology for Specifying and Tracing Requirements Engineering Artifacts and Test Artifacts

open access: yesCLEI Electronic Journal, 2019
This paper proposes an ontology that defines and integrates the concepts adopted for use cases and test cases specification. These concepts belong to the metamodels of different Requirements Engineering and testing management supporting tools, and their ...
María Luciana Roldán   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Determining Interdependencies among NFRs in Agile Environment to Reduce Conflicts

open access: yesEAI Endorsed Transactions on Mobile Communications and Applications, 2018
NFRs play a very key role in the development of high quality software. As NFRs are quality attributes of the software system, so it must be dealt properly and with care in the early phases of software development otherwise it will lead the system to ...
Jawad Ali   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Functional requirements decomposition in set-based design

open access: yesDesign Science
Designing systems is typically uncertain and ambiguous at the early stages. Set-based design (SBD) supports alternative exploration and gradual uncertainty reduction during the early lifecycle, making it practical for complex system design.
Minghui Sun   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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