Results 121 to 130 of about 10,881,624 (257)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Appendix A. Response of functional groups to plant diversity.

, 2016
Response of functional groups to plant ...
Kerri M. Crawford (2915438), Jennifer A. Rudgers (1898734)   +1 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Appendix D. Analysis of a type II functional response.

, 2016
Analysis of a type II functional ...
Nicolas Mouquet (143960), Dominique Gravel (98797), Frédéric Guichard (177600), Michel Loreau (60807)   +3 more
core   +1 more source

Stability and bifurcation in a delayed predator-prey system with stage structure and functional response

Electronic Journal of Differential Equations, 2009
In this paper, a delayed predator-prey system with stage structure and Holling type-II functional response is investigated. The local stability of a positive equilibrium and the existence of Hopf bifurcations are established. By using the normal form
Xiao Zhang, Rui Xu, Qintao Gan
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Biological Control Potential of the Reduviid Predator Rhynocoris fuscipes (Fabricius) in Managing Noctuid Pests: Insights Into Predation and Prey Preference

Insects
Understanding predator–prey and predator–predator interactions is essential for evaluating the effectiveness of biocontrol agents and developing efficient pest management strategies.
Chuanzhen Xue, Jiaying Mao, Bowen Xu, Lei Zhou, Haihang Zhou, Jianjun Mao, Zhongjian Shen, Lisheng Zhang, Mengqing Wang, Yuyan Li   +9 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Functional response models

, 2008
[[abstract]]We review functional regression models and discuss in more detail the situation where the predictor is a vector or scalar, such as a dose, and the response is a random trajectory. These models incorporate the influence of the predictor either
Chiou, JM; Muller, HG; Wang, JL
core