Results 81 to 90 of about 10,881,624 (257)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Are nutritional limitations in northern ungulates paradoxical?

Rangifer
Nutritional paradoxes are conclusions about nutritional ecology that seem counterintuitive or self-contradictory at first, but upon deeper investigation turn out to be well supported (i.e., they have a solution).
Kristin Denryter, Katherine L. Parker, Robert G. White   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Functional Response data

, 2016
Results of the functional response experiments. For each replicate the species, number of Daphnia, time elapsed in the feeding trial, initial density of Scenedesmus obliquus and final density of S.
Derek C. West (3300066), David M. Post (2906981), Post, David M., West, Derek C.   +3 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Stop-signal response inhibition in schizophrenia : Behavioural, event-related potential and functional neuroimaging data

, 2012
Inhibitory control deficits are well documented in schizophrenia, supported by impairment in an established measure of response inhibition, the stop-signal reaction time (SSRT).
Patricia Therese Michie, Matthew Edward Hughes, Fulham, William Ross, Hughes, Matthew Edward, Michie, Patricia Therese, Patrick James Johnston, Johnston, Patrick James, William Ross Fulham   +7 more
core   +1 more source

Preliminary Evaluation of the Biocontrol Potential of Stethorus punctillum, a Key Natural Enemy of Spider Mites in Northwest China

Agronomy
Spider mites are globally distributed pests that cause significant damage to a wide range of crops. The use of predators for the control of pest mites is an effective and environmentally sustainable strategy.
Haoyu Wang, Dawei Zhang, Huan Guo, Xiaoling He, Bing Liu, Senshan Wang, Yanhui Lu   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Nutrition/Dietetics Program's Response to Reviewers' Report

, 2012
Nutrition/Dietetics Program Response to Review Team ReportNutrition/Dietetics Program - Response to Reviewers' ReportNutrition/Dietetics Program - Academic Program ...
Academic Program Reivew, Nutrition/Dietetics Program, Response to Reviewers' Report   +1 more
core