Results 91 to 100 of about 2,663,164 (310)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Responsive functions and transport functions.
membrane, 1987 Switch-functionalized mambranes, the permeability of which can be controlled by triggers induced by light, heat, etc., have been developed. These mambranes were designed by combination of crown ethers which act as ion carriers with functional groups which accept a signal from the outside world.
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Response of an Apex Mammalian Predator to an Emergence of 13-Year Periodical Cicadas
AnimalsEmergences of periodical cicadas constitute intense, short-duration resource pulses that can produce significant functional and numerical responses among insectivorous species that prey on them. The response of coyotes, apex predators in Illinois USA, to
Brian L. Cypher
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Nonlinear impulse response functions [PDF]
Journal of Economic Dynamics and Control, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Marrying the merits of Nagelian reduction and functional reduction [PDF]
, 2011 This paper points out the merit of Nagelian reduction, namely to propose a model of inter-theoretic reduction that retains the scientific quality of the reduced theory, and the merit of functional reduction, namely to take multiple realization into ...
Christian Sachse +5 more
core +1 more source
Lung function and radiation response
The British Journal of Radiology, 1991 Abstract This study investigated whether impaired respiratory function affected the response to radiotherapy. A prospective study was performed in which lung function, arterial oxygen and haemoglobin concentration were examined, before treatment with radical radiotherapy, in 141 patients with advanced non-small cell lung cancer and head ...
A, Hong +4 more
openaire +2 more sources