Results 41 to 50 of about 585,080 (270)

The Evaluation of the Heart Failure Patient by Echocardiography: Time to go beyond the Ejection Fraction

Cardiovascular Innovations and Applications, 2015
Heart failure is a complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fill with or eject blood.
Jacqueline Dawson Dowe, Juan Vilaro, Karen Hamilton, Anita Szady, Juan M. Aranda   +4 more
doaj   +1 more source

Pulmonary Embolism After Vaginal Delivery in a Fontan Patient

JACC: Case Reports, 2020
The Fontan procedure was created to address the mixing of pulmonary and systemic venous return in patients with a single functional ventricle. The patient in this case with a Fontan repair experienced multiple pulmonary emboli 10 days post-partum.
Laura A. Keenahan, BS, Revanth K. Poondla, BS, Wayne J. Franklin, MD, Peter R. Ermis, MD, Pamela Ketwaroo, MD, Angeline Opina, MD, Manisha Gandhi, MD   +6 more
doaj   +1 more source

Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome

HGG Advances, 2023
Summary: Hypoplastic left heart syndrome (HLHS) is a severe congenital heart defect (CHD) characterized by hypoplasia of the left ventricle and aorta along with stenosis or atresia of the aortic and mitral valves.
Elizabeth E. Blue, Janson J. White, Michael K. Dush, William W. Gordon, Brent H. Wyatt, Peter White, Colby T. Marvin, Emmi Helle, Tiina Ojala, James R. Priest, Mary M. Jenkins, Lynn M. Almli, Jennita Reefhuis, Faith Pangilinan, Lawrence C. Brody, Kim L. McBride, Vidu Garg, Gary M. Shaw, Paul A. Romitti, Wendy N. Nembhard, Marilyn L. Browne, Martha M. Werler, Denise M. Kay, Seema Mital, Jessica X. Chong, Nanette M. Nascone-Yoder, Michael J. Bamshad   +26 more
doaj   +1 more source

Impact of Spironolactone on Endothelial Function in Patients with Single Ventricle Heart [PDF]

Congenital Heart Disease, 2009
Mid-term survivors of the Fontan procedure are at risk for progressive heart failure, and endothelial dysfunction is thought to contribute to this process. Aldosterone antagonism has been shown to improve survival in adults with heart failure and the effects are mediated in part by changes in endothelial function.
William T, Mahle, Alicia, Wang, Arshed A, Quyyumi, Michael E, McConnell, Wendy M, Book   +4 more
openaire   +2 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Right ventricular failure and pathobiology in patients with congenital heart disease – implications for long-term follow-up

Frontiers in Pediatrics, 2013
Right ventricular dysfunction represents a common problem in patients with congenital heart defects, such as Tetralogy of Fallot or pulmonary arterial hypertension.
Doreen eKöhler, Raoul eArnold, Tsvetomir eLoukanov, Matthias eGorenflo   +3 more
doaj   +1 more source

Atrioventricular Valve Regurgitation in Single Ventricle Heart Disease: A Common Problem Associated With Progressive Deterioration and Mortality

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
The Fontan procedure has provided patients with single ventricle physiology extended survival into adulthood and in many cases has improved their quality of life.
Stephanie Y. Tseng, Saira Siddiqui, Michael V. Di Maria, Garick D. Hill, Adam M. Lubert, Shelby Kutty, Alexander R. Opotowsky, Mathias Possner, David L. S. Morales, James A. Quintessenza, Tarek Alsaied   +10 more
doaj   +1 more source

Right ventricular visualization at SPECT perfusion imaging before and after revascularization in patients with postinfarction cardiosclerosis

Трансплантология (Москва), 2023
Aim. To evaluate the intersystemic (between the myocardium of the left coronary artery system and the right coronary artery system redistribution mechanisms of perfusion in the myocardium after revascularization in patients with coronary artery disease ...
E. N. Ostroumov, E. V. Migunova, E. D. Kotina, E. B. Leonova, I. M. Kuzmina, M. V. Parkhomenko, S. Yu. Kambarov, M. A. Sagirov   +7 more
doaj   +1 more source

Trajectories in Neurodevelopmental, Health-Related Quality of Life, and Functional Status Outcomes by Socioeconomic Status and Maternal Education in Children with Single Ventricle Heart Disease

Jornal de Pediatria, 2020
Trajectories of neurodevelopment and quality of life were analyzed in children with hypoplastic left heart syndrome according to socioeconomic status and maternal education.
E. Bucholz, L. Sleeper, R. Sananes, C. Brosig, C. Goldberg, S. Pasquali, J. Newburger   +6 more
semanticscholar   +1 more source