Results 81 to 90 of about 864,978 (298)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

FUNCTIONAL LANGUAGE STYLES:

open access: yesAnalele Universităţii "Dunărea de Jos" din Galaţi Fascicula XXIV Lexic comun / lexic specializat
In order to evaluate the use of neologisms, especially anglicisms from the contemporary Romanian language, our purpose is to imagine types of discourses or texts with the above-mentioned loans. We propose an analysis grid, designed with the caption ‘pragmatic-discursive space’ (PDS) to take into account ‘objective’ and ‘subjective’ guidelines in the ...
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Debata b le Issues in the Historiography of Colloquial Style

open access: yesStylistyka, 2020
This article is devoted to the main issues of elucidating the specifics colloąuial style in the modem theory of the literary language, presented in Slavic linguistics.

doaj  

Functional Styles and Language Functions

open access: yesPhilologica Jassyensia
The present study aims to analyze three distinct functional styles of language: conversational, scientific, and literary, examining the activation of language functions within each style and identifying their predominant function(s). We considered these three divergent linguistic registers to be equally compelling, given that their analytical units ...
openaire   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Theory of Explicit Substitutions with Safe and Full Composition

open access: yes, 2009
Many different systems with explicit substitutions have been proposed to implement a large class of higher-order languages. Motivations and challenges that guided the development of such calculi in functional frameworks are surveyed in the first part of ...
Delia Kesner   +4 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The grammar of traditional Malay long-roof type houses [PDF]

open access: yes, 2007
In this paper, the grammar of the traditional Malay houses (TMH) built in the past century is presented. The basic unit structures that form the shape of the TMH are first derived.
Said, Suzana
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy