Results 51 to 60 of about 888,994 (304)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

How can a multimodal approach to primate communication help us understand the evolution of communication? [PDF]

, 2013
Scientists studying the communication of non-human animals are often aiming to better understand the evolution of human communication, including human language.
Burrows, A., Liebal, Katja, Slocombe, K., Waller, Bridget   +3 more
core   +3 more sources

Nonparametric Functional Mapping of Quantitative Trait Loci [PDF]

Biometrics, 2009
SummaryFunctional mapping is a useful tool for mapping quantitative trait loci (QTL) that control dynamic traits. It incorporates mathematical aspects of biological processes into the mixture model‐based likelihood setting for QTL mapping, thus increasing the power of QTL detection and the precision of parameter estimation.
Yang, Jie, Wu, Rongling, Casella, George
openaire   +3 more sources

Testate Amoeba Functional Traits and Their Use in Paleoecology

Frontiers in Ecology and Evolution, 2020
This review provides a synthesis of current knowledge on the morphological and functional traits of testate amoebae, a polyphyletic group of protists commonly used as proxies of past hydrological changes in paleoecological investigations from peatland ...
Katarzyna Marcisz, Vincent E. J. Jassey, Anush Kosakyan, Valentyna Krashevska, Daniel J. G. Lahr, Enrique Lara, Łukasz Lamentowicz, Mariusz Lamentowicz, Andrew Macumber, Andrew Macumber, Yuri Mazei, Yuri Mazei, Edward A. D. Mitchell, Edward A. D. Mitchell, Nawaf A. Nasser, R. Timothy Patterson, Helen M. Roe, David Singer, Andrey N. Tsyganov, Andrey N. Tsyganov, Bertrand Fournier   +20 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Linking Aboveground Traits to Root Traits and Local Environment: Implications of the Plant Economics Spectrum. [PDF]

, 2019
The plant economics spectrum proposes that ecological traits are functionally coordinated and adapt along environmental gradients. However, empirical evidence is mixed about whether aboveground and root traits are consistently linked and which ...
Fang, Miao, Gilbert, Gregory S, Li, Wenbin, Lu, Huanping, Shen, Yong, Yu, Shixiao   +5 more
core  

Mechanisms of Surviving Burial: Dune Grass Interspecific Differences Drive Resource Allocation After Sand Deposition [PDF]

, 2018
Sand dunes are important geomorphic formations of coastal ecosystems that are critical in protecting human populations that live in coastal areas. Dune formation is driven by ecomorphodynamic interactions between vegetation and sediment deposition. While
Courtemanche R. P., Ehrenfeld J. G., Gleason H. A., Godfrey P. J., Hoagland D. R., Maun M. A., Mendelssohn I. A., Qu H., Scavia D., Stalter R., Vinent O. D.   +10 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Trait-based approaches to analyze links between the drivers of change and ecosystem services: Synthesizing existing evidence and future challenges [PDF]

, 2017
Understanding the responses of biodiversity to drivers of change and the effects of biodiversity on ecosystem properties and ecosystem services is a key challenge in the context of global environmental change.
Abelleira-Martínez, Abson, Balvanera, Balvanera, Bennett, Biggs, Biggs, Brown, Cadotte, Cardinale, Daniel, De Bello, De Lima, Dirzo, Dukes, Díaz, Díaz, Díaz, Fazey, Frimpong, García-Llorente, Gilroy, Goodness, Gossner, Grigulis, Gross, Hanski, Harrison, Hevia, Homburg, Hooper, Isbell, Kattge, Laliberté, Larsen, Lavorel, Lavorel, Lavorel, Lavorel, Lavorel, Mace, Mitchell, Moretti, Mori, Mouchet, Myers, Nagendra, Nahlik, Newbold, Nieto-Romero, Nimmo, Oliver, Pereira, Pereira, Peterson, Quétier, Radchuk, Ricketts, Seidl, Seppelt, Speight, Srivastava, Statzner, Storkey, Suding, Thompson, Valiente-Banuet, Vandewalle, Velasco, Verheyen, Vieira, Vihervaara, Violle, Vitousek, Wood   +74 more
core   +2 more sources

Describing mate preference functions and other function‐valued traits [PDF]

Journal of Evolutionary Biology, 2017
AbstractMate preferences are important causes of sexual selection. They shape the evolution of sexual ornaments and displays, sometimes maintaining genetic diversity and sometimes promoting speciation. Mate preferences can be challenging to study because they are expressed in animal brains and because they are a function of the features of potential ...
J T, Kilmer, K D, Fowler-Finn, D A, Gray, G, Höbel, D, Rebar, M S, Reichert, R L, Rodríguez   +6 more
openaire   +2 more sources