Results 61 to 70 of about 888,994 (304)
Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova +25 morewiley +1 more sourceTRY plant trait database - enhanced coverage and open access [PDF]
, 2020 Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits ...Aakala, T, Abedi, M, Acosta, ATR, Adamidis, GC, Adamson, K, Aiba, M, Albert, CH, Alcantara, JM, Alcazar, CC, Aleixo, I, Ali, H, Amiaud, B, Ammer, C, Amoroso, MM, Anand, M, Anderson, C, Anh, TDL, Anten, N, Antos, J, Apgaua, DMG, Ashman, TL, Asmara, DH, Asner, GP, Aspinwall, M, Atkin, O, Aubin, I, Baastrup-Spohr, L, Bahalkeh, K, Bahn, M, Baker, T, Baker, WJ, Bakker, JP, Baldocchi, D, Baltzer, J, Banerjee, A, Baranger, A, Barlow, J, Barneche, DR, Baruch, Z, Bastianelli, D, Battles, J, Bauerle, W, Bauters, M, Bazzato, E, Beckmann, M, Beeckman, H, Beierkuhnlein, C, Bekker, R, Belfry, G, Belluau, M, Beloiu, M, Benavides, R, Benomar, L, Berdugo-Lattke, ML, Berenguer, E, Bergamin, R, Bergmann, J, Berner, L, Bernhardt-Romermann, M, Bigler, C, Bjorkman, AD, Blackman, C, Blanco, C, Blonder, B, Blumenthal, D, Bocanegra-Gonzalez, KT, Boeckx, P, Bohlman, S, Bohning-Gaese, K, Boisvert-Marsh, L, Bond, W, Bond-Lamberty, B, Bonisch, G, Boom, A, Boonman, CCF, Bordin, K, Boughton, EH, Boukili, V, Bowman, DMJS, Bravo, S, Brendel, MR, Broadley, MR, Brown, KA, Bruelheide, H, Brumnich, F, Bruun, HH, Bruy, D, Buchanan, SW, Bucher, SF, Buchmann, N, Buitenwerf, R, Bunker, DE, Burger, J, Burrascano, S, Burslem, DFRP, Butterfield, BJ, Byun, C, Caccianiga, M, Cadotte, M, Cailleret, M, Camac, J, Camarero, JJ, Campany, C, Campetella, G, Campos, JA, Cano-Arboleda, L, Canullo, R, Carbognani, M, Carlucci, MB, Carvalho, F, Casanoves, F, Castagneyrol, B, Catford, JA, Cavender-Bares, J, Cerabolini, BEL, Cervellini, M, Chacon-Madrigal, E, Chapin, FS, Chapin, K, Chelli, S, Chen, AP, Chen, SC, Cherubini, P, Chianucci, F, Choat, B, Chung, KS, Chytry, M, Ciccarelli, D, Coll, L, Collins, CG, Conti, L, Coomes, D, Cornelissen, JHC, Cornwell, WK, Corona, P, Coyea, M, Craine, J, Craven, D, Cromsigt, JPGM, Csecserits, A, Cufar, K, Cuntz, M, da Silva, AC, Dahlin, KM, Dainese, M, Dalke, I, Dalle Fratte, M, Danihelka, J, Dannoura, M, Dawson, S, de Beer, AJ, de Dios, VR, De Frutos, A, de Gasper, AL, De Long, JR, Dechant, B, Delagrange, S, Delpierre, N, Derroire, G, Dias, AS, Diaz, S, Diaz-Toribio, MH, Dimitrakopoulos, PG, Dobrowolski, M, Doktor, D, Domingues, TF, Dong, N, Dransfield, J, Dressler, S, Drevojan, P, Duarte, L, Ducouret, E, Dullinger, S, Durka, W, Duursma, R, Dymova, O, E-Vojtko, A, Eckstein, RL, Ejtehadi, H, Elser, J, Emilio, T, Engemann, K, Erfanian, MB, Erfmeier, A, Esquivel-Muelbert, A, Esser, G, Estiarte, M, Fagan, WF, Fagundez, J, Falster, DS, Fan, Y, Fang, JY, Farris, E, Fazlioglu, F, Feng, YH, Fernandez-Mendez, F, Ferrara, C, Ferreira, J, Fidelis, A, Finegan, B, Firn, J, Flowers, TJ, Flynn, DFB, Fontana, V, Forey, E, Forgiarini, C, Francois, L, Frangipani, M, Frank, D, Frenette-Dussault, C, Freschet, GT, Fry, EL, Fyllas, NM, Gachet, S, Gallagher, R, Ganade, G, Ganga, F, Garcia-Palacios, P, Gargaglione, V, Garnier, E, Garrido, JL, Garvizu, GS, Gea-Izquierdo, G, Gibson, D, Gillison, AN, Giroldo, A, Glasenhardt, MC, Gleason, S, Gliesch, M, Goldberg, E, Goldel, B, Gonzalez-Akre, E, Gonzalez-Andujar, JL, Gonzalez-Melo, A, Gonzalez-Robles, A, Graae, BJ, Granda, E, Graves, S, Green, WA, Gregor, T, Gross, N, Guerin, GR, Gunther, A, Gutierrez, AG, Haddock, L, Haines, A, Hall, J, Hambuckers, A, Han, WX, Harrison, SP, Hattingh, W, Hawes, JE, He, PC, He, TH, Heberling, JM, Helm, A, Hempel, S, Hentschel, J, Herault, B, Heres, AM, Herz, K, Heuertz, M, Hickler, T, Hietz, P, Higuchi, P, Hipp, AL, Hirons, A, Hock, M, Hogan, JA, Holl, K, Honnay, O, Hornstein, D, Hou, EQ, Hough-Snee, N, Hovstad, KA, Ichie, T, Igic, B, Illa, E, Isaac, M, Ishihara, M, Ivanov, L, Ivanova, L, Iversen, CM, Izquierdo, J, Jackson, B, Jackson, RB, Jactel, H, Jagodzinski, AM, Jandt, U, Jansen, S, Jenkins, T, Jentsch, A, Jespersen, JRP, Jiang, GF, Johansen, JL, Johnson, D, Jokela, EJ, Joly, CA, Jordan, GJ, Joseph, GS, Junaedi, D, Junker, RR, Justes, E, Kabzems, R, Kane, J, Kaplan, Z, Kattenborn, T, Kattge, J, Kavelenova, L, Kearsley, E, Kempel, A, Kenzo, T, Kerkhoff, A, Khalil, MI, Kinlock, NL, Kissling, WD, Kitajima, K, Kitzberger, T, Kjoller, R, Klein, T, Kleyer, M, Klimesova, J, Klipel, J, Kloeppel, B, Klotz, S, Knops, JMH, Kohyama, T, Koike, F, Kollmann, J, Komac, B, Komatsu, K, Konig, C, Kraft, NJB, Kramer, K, Kreft, H, Kuhn, I, Kumarathunge, D, Kuppler, J, Kurokawa, H, Kurosawa, Y, Kuyah, S, Laclau, JP, Lafleur, B, Lallai, E, Lamb, E, Lamprecht, A, Larkin, DJ, Laughlin, D, Lavorel, S, Le Bagousse-Pinguet, Y, le Maire, G, le Roux, E, le Roux, PC, Leadley, P, Lee, T, Lens, F, Lewis, SL, Lhotsky, B, Li, XE, Li, YZ, Lichstein, JW, Liebergesell, M, Lim, JY, Lin, YS, Linares, JC, Liu, CJ, Liu, DJ, Liu, U, Livingstone, S, Llusia, J, Lohbeck, M, Lopez-Garcia, A, Lopez-Gonzalez, G, Lososova, Z, Louault, F, Lukacs, BA, Lukes, P, Luo, YJ, Lussu, M, Ma, SY, Mack, M, Maire, V, Makela, A, Makinen, H, Malhado, ACM, Mallik, A, Manning, P, Manzoni, S, Marchetti, Z, Marchino, L, Marcilio-Silva, V, Marcon, E, Marignani, M, Markesteijn, L, Marques, M, Martin, A, Martinez-Garza, C, Martinez-Vilalta, J, Maskova, T, Mason, K, Mason, N, Massad, TJ, Masse, J, Mayrose, I, Mazzochini, GG, McCarthy, J, McCormack, ML, McCulloh, K, McFadden, IR, McGill, BJ, McPartland, MY, Medeiros, JS, Medlyn, B, Meerts, P, Mehrabi, Z, Meir, P, Melo, FPL, Mencuccini, M, Meredieu, C, Messier, J, Meszaros, I, Metsaranta, J, Michaletz, ST, Michelaki, C, Migalina, S, Milla, R, Miller, JED, Minden, V, Ming, R, Mokany, K, Moles, AT, Molnar, VA, Molofsky, J, Molz, M, Montgomery, RA, Monty, A, Moravcova, L, Moreno-Martinez, A, Moretti, M, Mori, AS, Mori, S, Morris, D, Morrison, J, Mucina, L, Mueller, S, Muir, CD, Muller, SC, Munoz, F, Myers-Smith, IH, Myster, RW, Nagano, M, Naidu, S, Narayanan, A, Natesan, B, Negoita, L, Nelson, AS, Neuschulz, EL, Ni, J, Niedrist, G, Nieto, J, Niinemets, U, Nolan, R, Nottebrock, H, Nouvellon, Y, Novakovskiy, A, Nystuen, KO, O'Grady, A, O'Hara, K, O'Reilly-Nugent, A, Oakley, S, Oberhuber, W, Ohtsuka, T, Oliveira, R, Ollerer, K, Olson, ME, Onipchenko, V, Onoda, Y, Onstein, RE, Ordonez, JC, Osada, N, Ostonen, I, Ottaviani, G, Otto, S, Overbeck, GE, Ozinga, WA, Pahl, AT, Paine, CET, Pakeman, RJ, Papageorgiou, AC, Parfionova, E, Partel, M, Patacca, M, Paula, S, Paule, J, Pauli, H, Pausas, JG, Peco, B, Penuelas, J, Perea, A, Pereira, CMR, Peri, PL, Petisco-Souza, AC, Petraglia, A, Petritan, AM, Phillips, OL, Pierce, S, Pillar, VD, Pinho, BX, Pisek, J, Pomogaybin, A, Poorter, H, Portsmuth, A, Poschlod, P, Potvin, C, Pounds, D, Powell, AS, Power, SA, Prentice, IC, Prinzing, A, Puglielli, G, Pysek, P, Raevel, V, Rammig, A, Ransijn, J, Ray, CA, Reich, PB, Reichstein, M, Reid, DEB, Rejou-Mechain, M, Ribeiro, S, Richardson, S, Riibak, K, Rillig, MC, Riviera, F, Robert, EMR, Roberts, S, Robroek, B, Roddy, A, Rodrigues, AV, Rogers, A, Rollinson, E, Rolo, V, Romermann, C, Ronzhina, D, Roscher, C, Rosell, JA, Rosenfield, MF, Rossi, C, Roy, DB, Royer-Tardif, S, Ruger, N, Ruiz-Peinado, R, Rumpf, SB, Rusch, GM, Ryo, M, Sack, L, Saldana, A, Salgado-Negret, B, Salguero-Gomez, R, Santa-Regina, I, Santacruz-Garcia, AC, Santos, J, Sardans, J, Scalon, MC, Schamp, B, Scherer-Lorenzen, M, Schleuning, M, Schmid, B, Schmidt, M, Schmitt, S, Schneider, JV, Schowanek, SD, Schrader, J, Schrodt, F, Schuldt, B, Schurr, F, Semchenko, M, Seymour, C, Sfair, JC, Sharpe, JM, Sheppard, CS, Sheremetiev, S, Shiodera, S, Shipley, B, Shovon, TA, Siebenkas, A, Sierra, C, Silva, M, Silva, V, Sitzia, T, Sjoman, H, Slot, M, Smith, NG, Sodhi, D, Soltis, D, Soltis, P, Somers, B, Sonnier, G, Sorensen, MV, Sosinski, EE, Soudzilovskaia, NA, Souza, AF, Spasojevic, M, Sperandii, MG, Stan, AB, Stegen, J, Steinbauer, K, Stephan, JG, Sterck, F, Stojanovic, DB, Strydom, T, Suarez, ML, Svenning, JC, Svitkova, I, Svitok, M, Svoboda, M, Swaine, E, Swenson, N, Tabarelli, M, Takagi, K, Tappeiner, U, Tarifa, R, Tarin, T, Tautenhahn, S, Tauugourdeau, S, Tavsanoglu, C, te Beest, M, Tedersoo, L, Thiffault, N, Thom, D, Thomas, E, Thompson, K, Thornton, PE, Thuiller, W, Tichy, L, Tissue, D, Tjoelker, MG, Tng, DYP, Tobias, J, Torok, P, Torres-Ruiz, JM, Tothmeresz, B, Treurnicht, M, Trivellone, V, Trolliet, F, Trotsiuk, V, Tsakalos, JL, Tsiripidis, I, Tysklind, N, Umehara, T, Usoltsev, V. A., Vadeboncoeur, M, Vaezi, J, Valderrama, MY, Valladares, F, Vamosi, J, van Bodegom, PM, van Breugel, M, Van Cleemput, E, van de Weg, M, van der Merwe, S, van der Plas, F, van der Sande, MT, van Kleunen, M, Van Meerbeek, K, Vanderwel, M, Vanselow, KA, Varhammar, A, Varone, L, Vassilev, K, Vellend, M, Veneklaas, EJ, Verbeeck, H, Verheyen, K, Vibrans, A, Vieira, I, Villacis, J, Violle, C, Vivek, P, Wagner, K, Waldram, M, Waldron, A, Walker, AP, Waller, M, Walther, G, Wang, F, Wang, H, Wang, WQ, Watkins, H, Watkins, J, Weber, U, Weedon, JT, Wei, LP, Weigelt, P, Weiher, E, Wells, AW, Wellstein, C, Wenk, E, Werner, GDA, Westoby, M, Westwood, A, White, PJ, Whitten, M, Williams, M, Winkler, DE, Winter, K, Wirth, C, Womack, C, Wright, IJ, Wright, J, Wright, SJ, Ximenes, F, Yamada, T, Yamaji, K, Yanai, R, Yankov, N, Yguel, B, Zanini, KJ, Zanne, AE, Zeleny, D, Zhao, YP, Zheng, J, Zheng, JM, Zieminska, K, Zirbel, CR, Zizka, G, Zo-Bi, IC, Zotz, G +727 morecore Functional traits of fossil plants
New PhytologistSummaryA minuscule fraction of the Earth's paleobiological diversity is preserved in the geological record as fossils. What plant remnants have withstood taphonomic filtering, fragmentation, and alteration in their journey to become part of the fossil record provide unique information on how plants functioned in paleo‐ecosystems through their traits ...McElwain, Jennifer C., Matthaeus, William J., Barbosa, Catarina, Chondrogiannis, Christos, O' Dea, Katie, Jackson, Bea, Knetge, Antonietta B., Kwasniewska, Kamila, Nair, Richard, White, Joseph D., Wilson, Jonathan P., Montañez, Isabel P., Buckley, Yvonne M., Belcher, Claire M., Nogué, Sandra +14 moreopenaire +3 more sourcesRIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz +9 morewiley +1 more sourceSingle Grazing Is More Detrimental to Grasslands Than Mixed Grazing: Evidence From the Response of Functional Traits of Dominant Plants to Grazing Systems
Frontiers in Ecology and Evolution, 2021 Plant functional traits reflect species ecological strategies and determine how plants respond to environmental changes, however, how dominant species in the Inner Mongolia grassland adapt to different grazing systems by changing their functional traits ...Zheng Wang, Jinghui Zhang, Jinghui Zhang, Zhiyong Li, Huamin Liu, Lixin Wang, Lixin Wang, Wen Wang, Yang Wang, Cunzhu Liang +9 moredoaj +1 more sourceCOMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom +6 morewiley +1 more sourceTen years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post-genome era. [PDF]
, 2019 The horse reference genome from the Thoroughbred mare Twilight has been available for a decade and, together with advances in genomics technologies, has led to unparalleled developments in equine genomics.Bellone, R, Finno, Carrie, Petersen, J, Raudsepp, T +3 morecore +2 more sources