Results 211 to 220 of about 934,400 (317)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Correction: Caretaker-reported quality of life, functionality, and complications associated with assistive mobility cart use in companion animals. [PDF]

Front Vet Sci
Frontiers Production Office.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Adaptive Level Control Systems - Research on Maximizing Stormwater Pond Functionality: Final Report

In urban settings, space for new stormwater features at grade is often limited, and building new underground systems can be prohibitively expensive. In these cases, retrofitting existing stormwater infrastructure with Adaptive Level Control Systems (ALCS)
Anderson, Cory, Stratton, Sarah
core  

Reduced-crosstalk antennas for grating-lobe-free and wide-field-of-view integrated optical phased arrays. [PDF]

Nat Commun
Crawford-Eng H, Garcia Coleto A, Mazur BM, DeSantis DM, Sneh T, Notaros J.   +5 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effectiveness of kinesio tape in people with low back pain. A systematic review with meta-analysis. [PDF]

Eur J Phys Rehabil Med
Inostroza-Quiroz J, Solano-López R, Bascour-Sandoval C, Buitrago-García D, Salazar J, Huaiquilaf-Jorquera S, Rodríguez M, Oliveros MJ, Serón P.   +8 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Correction: Scientific validation of traditionally used omija (Schisandra chinensis) extract mixture for postprandial glucose regulation

Journal of Ethnic Foods
Hye Jeong Yang, Min Jung Kim, Hak Yong Lee, Dai Ja Jang, Sunmin Park   +4 more
doaj   +1 more source

Efficient multi-party private set union resistant to maximum collusion attacks. [PDF]

Sci Rep
Liu Q, Lee JW.
europepmc   +1 more source