Results 51 to 60 of about 121,679 (298)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Boundary element method applied to the bending analysis of thin functionally graded plates

Latin American Journal of Solids and Structures
The present work introduces the boundary element method applied to the bending analysis of functionally graded plates. It is assumed that material properties are graded through the thickness direction of the plate according to a power law distribution ...
A. R. Damanpack, M. Bodaghi, H. Ghassemi, M. Sayehbani   +3 more
doaj   +1 more source

Fabrication of Ceramic-Metal Functionally Graded Materials [PDF]

Engineering and Technology Journal, 2013
High order step wise functionally graded materials Al2O3-Ti are fabricated. These materials combine the high fracture toughness of Ti phase and the relatively low density of Al2O3 and stand for candidate materials for harsh mechanical and thermal ...
Alaa A. Atiyah, Saad. B. H. Farid, Dheya N. Abdulamer   +2 more
doaj   +1 more source

Laser melting functionally graded composition of Waspaloy((R)) and Zirconia powders [PDF]

, 2007
An approach for fabricating functionally graded specimens of supernickel alloy and ceramic compositions via Selective Laser Melting (SLM) is presented. The focus aimed at using the Functionally Graded Material (FGM) concept to gradually grade powdered ...
Hopkinson, N., Mumtaz, K.A.
core   +2 more sources

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Acoustic radiation characteristics of FG cylindrical shell based on Jacobi-Ritz modified boundary element method

Journal of Low Frequency Noise, Vibration and Active Control
In this paper, a semi-analytic method based on Jacobi-Ritz modified boundary element is proposed to solve the acoustic radiation response of functionally graded cylindrical shell.
Jiajun Zheng, Yuhang Tang, Haichao Li, Zhe Zhao, Fuzhen Pang, Cong Gao   +5 more
doaj   +1 more source

Theoretical Predictions on Mechanical Properties of Functionally Graded Epoxy/Clay Nanocomposites [PDF]

International Journal of Advanced Design and Manufacturing Technology, 2020
In this paper, the theoretical predictions of mechanical properties of functionally graded and uniform distributions Epoxy/clay nanocomposites are presented. The specimens were prepared for uniformly distribution of nanoclay with different nano particles
Mahdi Karami Khorramabadi
doaj  

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

A new sinusoidal shear deformation theory for bending, buckling, and vibration of functionally graded plates [PDF]

, 2012
A new sinusoidal shear deformation theory is developed for bending, buckling, and vibration of functionally graded plates. The theory accounts for sinusoidal distribution of transverse shear stress, and satisfies the free transverse shear stress ...
Ameur, Atmane, Aydogdu, Benyoucef, Bodaghi, Della Croce, Fares, Ganapathi, Hosseini-Hashemi, Hosseini-Hashemi, Hosseini-Hashemi, Huu-Tai Thai, Javaheri, Karama, Kitipornchai, Lee, Liew, Mantari, Matsunaga, Meiche, Merdaci, Mohammadi, Naderi, Pradyumna, Qatu, Reddy, Shufrin, Talha, Talha, Thuc P. Vo, Xiang, Xiao, Yang, Zenkour, Zenkour, Zenkour, Zhang, Zhao, Zhao   +38 more
core   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source