Results 111 to 120 of about 80,406 (296)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Large amplitude vibration of doubly curved FG-GRC laminated panels in thermal environments

Nanotechnology Reviews, 2019
A study on the large amplitude vibration of doubly curved graphene-reinforced composite (GRC) laminated panels is presented in this paper. A doubly curved panel is made of piece-wise GRC layers with functionally graded (FG) arrangement along the ...
Shen Hui-Shen, Xiang Yang, Fan Yin
doaj   +1 more source

Analytical Solution of Thermo-Mechanical Properties of Functionally Graded Materials by Asymptotic Homogenization Method. [PDF]

Materials (Basel), 2022
Chen D, Liu L, Chu L, Liu Q.
europepmc   +1 more source

Spectral representation of the effective dielectric constant of graded composites

, 2005
We generalize the Bergman-Milton spectral representation, originally derived for a two-component composite, to extract the spectral density function for the effective dielectric constant of a graded composite.
A. Kawasaki, D. J. Bergman, G. W. Milton, G. W. Milton, J. B. Holt, J. D. Jackson, K. W. Yu, L. Dong, M. Yamanouchi, Mikko Karttunen   +9 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Influence of Thermal Sensitivity of Functionally Graded Materials on Temperature during Braking. [PDF]

Materials (Basel), 2022
Yevtushenko A, Topczewska K, Zamojski P.
europepmc   +1 more source

Linear And Nonlinear Thermoelastic Analysis Of Functionally Graded Materials Axisymmetric Rotating Disks [PDF]

, 2008
Functionally graded materials (FGMs) are non-homogeneous materials where the volume fraction of two or more materials is varied, as a power-law distribution, continuously as a function of position along certain dimension(s) of the structure.
Bayat, Mehdi
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Thermoelastic interactions in functionally graded materials without energy dissipation

Curved and Layered Structures
This study addresses the problem of thermoelastic interaction in functionally graded isotropic unbounded media owing to a timed pulse within the framework of generalized thermoelastic theory without energy dissipation (TEWOED).
Alqahtani Zuhur, Abbas Ibrahim, El-Bary Alaa A., Almuneef Areej   +3 more
doaj   +1 more source

Spark Plasma Sintering of AlN/Al Functionally Graded Materials. [PDF]

Materials (Basel), 2021
Xiu Z, Ju B, Liu S, Song Y, Du J, Li Z, Zhou C, Yang W, Wu G.   +8 more
europepmc   +1 more source