Results 111 to 120 of about 79,019 (297)

Role of additive manufacturing in developing functionally graded materials for nuclear applications

Frontiers in Nuclear Engineering
The global acceptance of additive manufacturing has evolved with time and has proven to provide promising solutions to varied critical requirements of the nuclear industry.
Amal Sasi, Madhulika Srivastava, K. Dash
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Large amplitude vibration of doubly curved FG-GRC laminated panels in thermal environments

Nanotechnology Reviews, 2019
A study on the large amplitude vibration of doubly curved graphene-reinforced composite (GRC) laminated panels is presented in this paper. A doubly curved panel is made of piece-wise GRC layers with functionally graded (FG) arrangement along the ...
Shen Hui-Shen, Xiang Yang, Fan Yin
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Three-Dimensional Fracture Analysis in Functionally Graded Materials Using the Finite Block Method in Strong Form. [PDF]

Materials (Basel), 2023
Fu CY, Yang Y, Zhou YR, Shi CZ, Wen PH.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Thermoelastic interactions in functionally graded materials without energy dissipation

Curved and Layered Structures
This study addresses the problem of thermoelastic interaction in functionally graded isotropic unbounded media owing to a timed pulse within the framework of generalized thermoelastic theory without energy dissipation (TEWOED).
Alqahtani Zuhur, Abbas Ibrahim, El-Bary Alaa A., Almuneef Areej   +3 more
doaj   +1 more source

Latest Developments to Manufacture Metal Matrix Composites and Functionally Graded Materials through AM: A State-of-the-Art Review. [PDF]

Materials (Basel), 2023
Ostolaza M, Arrizubieta JI, Lamikiz A, Plaza S, Ortega N.   +4 more
europepmc   +1 more source

Linear And Nonlinear Thermoelastic Analysis Of Functionally Graded Materials Axisymmetric Rotating Disks [PDF]

, 2008
Functionally graded materials (FGMs) are non-homogeneous materials where the volume fraction of two or more materials is varied, as a power-law distribution, continuously as a function of position along certain dimension(s) of the structure.
Bayat, Mehdi
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source