Geometrically Nonlinear Vibrations of Functionally Graded Shallow Shells [PDF]
An original method for investigation of geometrically nonlinear vibrations of functionally graded shallow shells and plates with complex planform is presented. Shells under consideration are made from a composite of ceramics and metal.
Bhaskar, A., Shmatko, T.
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The Effect of Functionally Graded Materials on Temperature during Frictional Heating at Single Braking. [PDF]
Yevtushenko A, Topczewska K, Zamojski P.
europepmc +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Vibration Analysis of a Tetra-Layered FGM Cylindrical Shell Using Ring Support
In the present study, the vibration characteristics of a cylindrical shell (CS) made up of four layers are investigated. The ring is placed in the axial direction of a four-layered functionally graded material (FGM) cylindrical shell. The layers are made
Asra Ayub +3 more
doaj +1 more source
Natural Frequencies Optimization of Thin-Walled Circular Cylindrical Shells Using Axially Functionally Graded Materials. [PDF]
Alshabatat NT.
europepmc +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The Effect of Functionally Graded Materials on Temperature during Frictional Heating: Under Uniform Sliding. [PDF]
Yevtushenko A, Topczewska K, Zamojski P.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Crack Growth Simulation of Functionally Graded Materials Based on Improved Bond-Based Peridynamic Model. [PDF]
Min L, Liu Q, Liu L.
europepmc +1 more source

