The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang +13 more
wiley +1 more source
Analysis of thermal wave scattering and temperature distribution in sub-surface, defects of gradient construction materials. [PDF]
Yang X +8 more
europepmc +1 more source
Multimodal Structural Color Graphics Based on Colloidal Photonic Microdome Arrays
A hybrid photonic system combining colloidal crystals and microscale domes is designed to achieve four switchable optical states via the interplay of Bragg reflection and TIR interference. The graphics composed of the photonic microdome arrays provide tunable, angle‐sensitive structural coloration and concealed‐to‐revealed transitions, offering a ...
Jun‐Gu Kang +4 more
wiley +1 more source
Spatiotemporal mapping of osteomyelitis pathogenesis guides the design of functionally graded bone regeneration scaffolds. [PDF]
Wang C +11 more
europepmc +1 more source
Enzymatically crosslinked gelatin‐based organohydrogels, fabricated through a fully bio‐based and scalable process, exhibit exceptional strain and temperature sensing capabilities with minimal interference from environmental humidity. These transparent, stretchable, and ionically conductive materials operate without synthetic fillers or dopants.
Pietro Tordi +7 more
wiley +1 more source
Numerical Optimization of Functionally Graded Ti-HAP Material for Tibial Bone Fixation System. [PDF]
Szymkiewicz K.
europepmc +1 more source
Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source
Size-dependent static response of a functionally graded nanobeam attached to a piezoelectric fibre-reinforced composite actuator. [PDF]
Alghanmi RA.
europepmc +1 more source
Mesoporous Carbon Thin Films with Large Mesopores as Model Material for Electrochemical Applications
Mesoporous carbon thin films possessing 70 nm mesopores are prepared on titanium substrates by soft templating of resol resins with a self‐synthesized poly(ethylene oxide)‐block‐poly(hexyl acrylate) block copolymer. A strategy to avoid corrosion of the metal substrate is presented, and the films are extensively characterized in terms of morphology ...
Lysander Q. Wagner +9 more
wiley +1 more source
Phased Array Ultrasonic Testing of W/EUROFER Functionally Graded Coating. [PDF]
Mishra AK, Aktaa J.
europepmc +1 more source

