Results 61 to 70 of about 38,875 (281)

Investigation of the Static Bending Response of FGM Sandwich Plates [PDF]

Journal of Applied and Computational Mechanics
In the present work, a displacement-based high-order shear deformation theory is introduced for the static response of functionally graded plates. The present theory is variationally consistent and strongly similar to the classical plate theory in many ...
Lazreg Hadji, Vagelis Plevris, George Papazafeiropoulos   +2 more
doaj   +1 more source

A New Sinusoidal Shear Deformation Theory for Static Bending Analysis of Functionally Graded Plates Resting on Winkler–Pasternak Foundations

Advances in Civil Engineering, 2021
In this article, a new sinusoidal shear deformation theory was developed for static bending analysis of functionally graded plates resting on elastic foundations.
Pham Minh Phuc, Vu Nguyen Thanh
doaj   +1 more source

Thermally Induced Bistable Functionally Graded Nanocomposite Plate

Mathematical Problems in Engineering, 2022
This paper explores the feasibility of using functionally graded carbon nanotube-reinforced composite (FG-CNTRC) in designing bistable plates. Single-walled carbon nanotubes (SWCNTs) in this nanocomposite are assumed to have a functionally graded distribution across the thickness direction following a power law. By varying the distribution type, volume
Yantao Zhu, Jixiao Tao
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Gradient design of metal hollow sphere (MHS) foams with density gradients [PDF]

, 2012
This is the post-print version of the final paper published in Composites Part B: Engineering. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Liu, Y, Wang, B, Wu, H-X
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Influence of porosity on the analysis of sandwich plates FGM using of high order shear-deformation theory.

Fracture and Structural Integrity, 2020
In this article, the analytical solutions for static of bending analysis of functionally graded sandwich plates using four-variable high order shear-deformation theory is presented.
Slimane Merdaci, Adda Hadj Mostefa
doaj   +1 more source

Computational modeling of sigmoid functionally graded material (SFGM) plate

Materials Research Express, 2023
The first-order shear deformation theory (FSDT) was used to explore the natural frequency response of functionally graded piezoelectric plates subjected to static electrical and mechanical strain in this present study.
Jai Kumar Sharma, Sateesh Kumar, Nishant Kumar, S M Mozammil Hasnain, Shatrudhan Pandey, Ahmed Farouk Deifalla, Adham E Ragab   +6 more
doaj   +1 more source

Bending and vibration of functionally graded material sandwich plates using an accurate theory

, 2012
In this paper, the bending and the free flexural vibration behaviour of sandwich functionally graded material (FGM) plates are investigated using QUAD-8 shear flexible element developed based on higher order structural theory.
Ali, Anderson, Bhangale, Das, Ferreira, Ganapathi, Ganapathi Manickam, Koizumi, Li, Makhecha, Murukami, Natarajan, Nosier, Pan, Reddy, Roderigues, S. Natarajan, Shen, Singh, Vel, Zenkour, Zenkour   +21 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source