Results 41 to 50 of about 11,682,338 (289)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

UM171 cooperates with PIM1 inhibitors to restrict HSC expansion markers and suppress leukemia progression

Cell Death Discovery, 2022
The pyrimido-indole derivative UM171 promotes human Hematopoietic Stem Cells Expansion (HSCE), but its impact on leukemia is not known. Herein, we show in a mouse model of erythroleukemia that UM171 strongly suppresses leukemia progression.
Anling Hu, Jian Gao, Krishnapriya M. Varier, Babu Gajendran, Fei Jiang, Wuling Liu, Chunlin Wang, Xiao Xiao, Yanmei Li, Eldad Zacksenhaus, Sajjad Ali, Yaacov Ben-David   +11 more
doaj   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Demographic and environmental factors associated with disability in India, Laos, and Tajikistan: a population-based cross-sectional study

BMC Public Health, 2022
Background The number of people experiencing functional limitations due to health conditions (capacity) is expected to increase in low and middle-income countries as populations age and rates of non-communicable disease rise.
Michael Zhu Chen, Lindsay Lee, Carolina Fellinghauer, Alarcos Cieza, Somnath Chatterji   +4 more
doaj   +1 more source

Nearly hyperharmonic functions are infima of excessive functions

, 2019
Let $\mathfrak X$ be a Hunt process on a locally compact space $X$ such that the set $\mathcal E_{\mathfrak X}$ of its Borel measurable excessive functions separates points, every function in $\mathcal E_{\mathfrak X}$ is the supremum of its continuous ...
Hansen, Wolfhard, Netuka, Ivan
core   +1 more source

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi, Paula D. Robinson, Shana Jacobs, L. Lee Dupuis, the International Pediatric Dexamethasone Panel, Sameer Bakhshi, Tiene Bauters, Eva Brack, Simone Cesaro, Claire Fosbrook, Jason Freedman, Tamara MacDonald, Eloise Neumann, Venkatraman Radhakrishnan, Rod Rassekh, Florian Slimano, Johnathan Soggee, Joel Thompson, Marianne van de Wetering, Milena Villarroel, Jasper Wong   +20 more
wiley   +1 more source

ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genes

BMC Cancer, 2021
Background Cholesterol plays vital roles in human physiology; abnormal levels have deleterious pathological consequences. In cancer, elevated or reduced expression of cholesterol biosynthesis is associated with good or poor prognosis, but the underlying ...
Fang Yu, Babu Gajendran, Ning Wang, Klarke M. Sample, Wuling Liu, Chunlin Wang, Anling Hu, Eldad Zacksenhaus, Xiaojiang Hao, Yaacov Ben-David   +9 more
doaj   +1 more source

Lyapunov functions via Whitney's size functions [PDF]

, 2014
In this paper we present a technique for constructing Lyapunov functions based on Whitney's size functions. Applications to asymptotically stable equilibrium points, isolated sets, expansive homeomorphisms and continuum-wise expansive homeomorphisms are ...
Artigue, Alfonso
core  

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Structural and Vascular Features of Macula Related to the Recurrence of Macular Edema in Central Retinal Vein Occlusion After Anti-VEGF Therapy

Journal of Ophthalmology
Conclusion: With prolonged CRVO duration, more anti-VEGF injections, and more retinal photocoagulation procedures, retinal, choroidal, and vascular atrophy in the macula occurs in CRVO eyes, making ME less likely to recur.
Dazhuang Ren, Cece Zhao, Gaoxu Wei, Xiaoyun Hou, Chang Li, Zhiqing Li   +5 more
doaj   +1 more source