Results 51 to 60 of about 895 (256)

On the entropy conditions for some flux limited diffusion equations

open access: yes, 2011
In this paper we give a characterization of the notion of entropy solutions of some flux limited diffusion equations for which we can prove that the solution is a function of bounded variation in space and time.
V. Caselles, Caselles, V.
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Note on Ostrowski's Inequality

open access: yes, 2002
This paper deals with the problem of estimating the deviation of the values of a function from its mean value. We consider the following special cases: i) the case of random variables (attached to arbitrary probability fields); ii) the comparison is ...
Florea, Aurelia, Niculescu, Constantin P
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Generalizations of Weighted Trapezoidal Inequality for Monotonic Mappings and Its Applications

open access: yes, 2003
In this paper, we establish some generalizations of weighted trapezoid inequality for monotonic mappings, and give several applications for r − moment, the expectation of a continuous random variable and the Beta ...
Yang, Gou-Sheng   +2 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Alternate characterizations of bounded variation and of general monotonicity for functions [PDF]

open access: yesIllinois Journal of Mathematics, 2016
We find necessary and sufficient conditions for a function to be equal almost everywhere to a function of bounded variation. These results can be applied to broaden the class of general monotone functions.
openaire   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

A Generalisation of the Trapezoidal Rule for the Riemann-Stieltjes Integral and Applications

open access: yes, 2000
A generalisation of the trapezoid rule for the Riemann-Stieltjes integral and applications for special means are ...
Boldea, Marius Valentin   +5 more
core  

Home - About - Disclaimer - Privacy