Results 21 to 30 of about 27,129 (305)
On new Milne-type inequalities for fractional integrals
In this study, fractional versions of Milne-type inequalities are investigated for differentiable convex functions. We present Milne-type inequalities for bounded functions, Lipschitz functions, functions of bounded variation, etc., found in the ...
Hüseyin Budak +2 more
doaj +1 more source
Computable Jordan Decomposition of Linear Continuous Functionals on $C[0;1]$ [PDF]
By the Riesz representation theorem using the Riemann-Stieltjes integral, linear continuous functionals on the set of continuous functions from the unit interval into the reals can either be characterized by functions of bounded variation from the unit ...
Klaus Weihrauch, Tahereh Jafarikhah
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Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
On functions of bounded variation [PDF]
AbstractThe recently introduced concept of ${\mathcal D}$-variation unifies previous concepts of variation of multivariate functions. In this paper, we give an affirmative answer to the open question from [20] whether every function of bounded Hardy–Krause variation is Borel measurable and has bounded ${\mathcal D}$-variation.
Aistleitner, Christoph +3 more
openaire +3 more sources
Perturbed Companions of Ostrowski’s Inequality for Absolutely Continuous Functions (I)
Perturbed companions of Ostrowski’s inequality for absolutely continuous functions whose derivatives are either bounded or of bounded variation and applications are given.
Dragomir Silvestru Sever
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Impulsive Control Systems with Trajectories of Bounded p-Variation
The paper deals with impulse-trajectory relaxations of control-affine systems under the assumption that $L_1$-norms of the control functions are not uniformly bounded. Generalized solutions of such control systems may be of infinite total variation. Most
O.N. Samsonyuk, M. V. Staritsyn
doaj +1 more source

