Results 41 to 50 of about 27,805 (255)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Functions with bounded E-d-variation on undirected tree networks

open access: yesJournal of Numerical Analysis and Approximation Theory, 2002
In this paper we define and study functions with bounded \(E-d\)-variation on undirected tree networks. For these functions with bounded \(E-d\)-variation we establish a Jordan type theorem.
Daniela Marian
doaj   +2 more sources

On the Nemytskii Operator in the Space of Functions of Bounded (p, 2, α)-Variation with Respect to the Weight Function

open access: yesDemonstratio Mathematica, 2014
In this paper, we consider the Nemytskii operator (Hf)(t) = h(t, f(t)), generated by a given function h. It is shown that if H is globally Lipschitzian and maps the space of functions of bounded (p,2,α)-variation (with respect to a weight function α ...
Aziz Wadie
doaj   +1 more source

Optimal Integration for Functions of Bounded Variation [PDF]

open access: yesMathematics of Computation, 1985
The unique optimal information and the unique optimal linear algorithm are obtained for the integration of functions of bounded variation.
Traub, Joseph F., Lee, David
openaire   +4 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

On functions of bounded n-th variation [PDF]

open access: yesFundamenta Mathematicae, 1988
Following an idea of \textit{W. L. C. Sargent} [Proc. Lond. Math. Soc., II. Ser. 47, 212-247 (1941; Zbl 0061.102); ibid. 52, 365-376 (1951; Zbl 0045.332)], the authors introduce concepts of higher order bounded variation using Peano derivatives; denote these by \(V_ nB,\quad V_ nB^*,\) and the associated generalized classes by \(V_ nBG,\quad V_ nBG^*.\)
Mukhopadhyay, S. N., Sain, D. N.
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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