Results 81 to 90 of about 8,493,253 (253)

European Union Agency for Fundamental Rights: Violence Against Women Survey, 2012

open access: yes, 2015
copyright UK Data Service and data collection copyright owner.The European Union Agency for Fundamental Rights (FRA) has carried out the first survey on women's experiences of violence across the 28 Member States of the European Union (EU).
European Union Agency for Fundamental Rights (FRA)
core   +3 more sources

Auxiliary identification of depression patients using interpretable machine learning models based on heart rate variability: a retrospective study

open access: yesBMC Psychiatry
Objective Depression has emerged as a global public health concern with high incidence and disability rates, which are timely imperative to identify and intervene in clinical practice.
Min Yang   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Differentiaalmeetkunde in de getaltheorie [PDF]

open access: yes, 2014
Voor getaltheorie is geen enkel soort wiskunde te min; de koningin onder de wiskundedisciplines heeft combinatoriek, algebra en algebraïsche meetkunde gebruikt, complexe analyse, representatietheorie, Lie-theorie, ergodentheorie, grootschalig rekenen ...
Fundamental mathematics   +2 more
core  

On the Brauer-Manin obstruction for degree-four del Pezzo surfaces [PDF]

open access: yes, 2016
We show that for every integer 1≤d≤4 and every finite set S of places, there exists a degree-d del Pezzo surface X over Q such that Br(X)/Br(Q)≅Z/2Z and the nontrivial Brauer class has a nonconstant local evaluation exactly at the places in S.
Fundamental mathematics   +3 more
core   +2 more sources

Fracture Problems in Graded Magneto-Electro-Elastic Half-Plane by Boundary Integral Equations

open access: yesEngineering Proceedings
A boundary integral equations method (BIEM) for a graded magneto-electro-elastic (MEE) half-plane with cracks under an incident time-harmonic SH wave is presented.
Yonko Stoynov
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Fundamental Understanding of Magnetic Reconnection via Spiral CT Scan. VIII. Electron Distribution Function

open access: yesThe Astrophysical Journal
For the first time, we reveal the spatial evolution of electron distribution functions around a reconnection X-line, by using the spiral CT scan technique, which is a novel technique analogous to that used in hospitals. This X-line was detected by NASA’s
H. S. Fu, Z. Wang, J. B. Cao
doaj   +1 more source

Fundamental Processes in Renal Function Discovered at the Mt. Desert Island Biological Laboratory

open access: yesKidney360
Some 25 years after its founding as a marine laboratory in 1898 by Tufts University, The Mt. Desert Island Biological Laboratory (MDIBL) became a center for advances in renal physiology for the next 90 years.
David H. Evans   +2 more
doaj   +1 more source

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