Results 81 to 90 of about 6,143,449 (300)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Children’s Fundamental Movement Skills, Social Emotional Development and Physical Activity Development Based on Kids’ Athletics Intervention: SEM Modelling and Analysis

open access: yesPhysical Education Theory and Methodology
Objectives. This study aimed to examine the developmental status of fundamental movement skills, social emotional development, and physical activity in Chinese children aged 7 to 10.
Chenhua Huang, Chairat Choosakul
doaj   +1 more source

Exploring Recommendations for Child and Adolescent Fundamental Movement Skills Development: A Narrative Review

open access: yesInternational Journal of Environmental Research and Public Health, 2023
Fundamental movement skills (FMS) are frequently referred to as the “building blocks” of movement for children and adolescents in their lifelong physical activity journey. It is critical, however, that FMS are developed within Physical Education learning
Wesley O'Brien   +5 more
semanticscholar   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Fundamental Movement Skills among Iranian Primary School Children.

open access: yesJournal of Family and Reproductive Health, 2014
To determine the relationship between anthropometric indicators, physical activity (PA) and socioeconomic status (SES) with fundamental movement skills (FMS) among Iranian male students.In this descriptive study, based on SES scores, 241 students (7-10 ...
Bahman Aalizadeh   +2 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Multilateral Motion Analysis in Elementary School Students Using Fundamental Movement Skill Method based on Territory

open access: yesJurnal Pendidikan Jasmani dan Olahraga
Developing Fundamental Movement Skills (FMS) is critical for a child physical, cognitive, and social growth. While previous studies have explored FMS in general, the influence of territorial environments remains underexamined.
Muhamad Syafei   +5 more
doaj   +1 more source

Prevalence Distribution of Fundamental Movement Skills in Children of Tehran Elementary Schools [PDF]

open access: yesرشد و یادگیری حرکتی ورزشی, 2016
Fundamental movement skills are observable patterns of motor behaviors including locomotor, manipulative, and stability activities. The aim of this study was to assess the gross motor development and the movement skill proficiency in elementary school ...
Hamid Salehi, Mahshid Zarezade
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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