Comprehensive analysis of structural parameters influencing the fundamental period of steel-braced RC buildings using machine learning interpretability [PDF]
Taimur Rahman +2 more
openalex +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Neutrino magnetic moments: effective versus fundamental parameters
Nuclear Physics BThe search for neutrino magnetic moments offers a valuable window into physics beyond the Standard Model. However, a common misconception arises in the interpretation of experimental results: the assumption that the so-called effective neutrino magnetic ...
Christoph A. Ternes, Mariam Tórtola
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Fundamental parameters of the developing thymic epithelium in the mouse. [PDF]
Sci Rep, 2018 Hirakawa M +8 more
europepmc +1 more source
PCA-based inversion of stellar fundamental parameters from high-resolution Echelle spectra [PDF]
, 2014 F. Paletou, J.-F. Trouilhet, T. Boehm
openalex +1 more source
Fundamental parameters and stellar evolution
, 2004 Some discrepancies have been pointed by various authors (Popper 1997, Torres & Ribas 2002) in the past few years between stellar evolution model predictions in the 0.7 - 1.1 M⊙ mass range and results obtained from binary stars with the most accurately known properties.
Oblak, E. +4 more
openaire +3 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
An Implementation of the Fundamental Parameters Approach for Analysis of X-ray Powder Diffraction Line Profiles. [PDF]
J Res Natl Inst Stand Technol, 2015 Mendenhall MH, Mullen K, Cline JP.
europepmc +1 more source