Results 101 to 110 of about 8,532,574 (316)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Consolidation of Arguments in favor of the Right of Access to Public Information as a Fundamental Right

open access: yesAge of Human Rights Journal, 2017
Analysis of the doctrinal position regarding the nature of the right of access to public information and the development of new arguments that reinforce and consolidate its fundamental nature.
Manuel Palomares Herrera
doaj   +1 more source

Mass generation of elementary particles and origin of the fundamental forces in algebraic quantum theory [PDF]

open access: yes, 2007
The main thesis of this paper deals with the interactions of a set of fermions which are described by one basic type of bilinear interactions,two symmetric semiobjects,three embedded shells and four fundamental (strong) gravito-electro-magnetic forces ...
Pierre, C.
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Considerations on the Right to Asylum [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2016
Hugo Grotius, considered one of the fathers of public international law, was the one who triedsince 1625 to define the concept of asylum in the legal sphere in his writings, especially in his work"De jure belli ac pacis."While internationally there is no
Florica Brasoveanu
doaj  

The Right to Bear Arms: A Uniquely American Entitlement [PDF]

open access: yes, 2010
In District of Columbia v. Heller the Supreme Court held that individuals have a constitutional right to own firearms, notably to keep a loaded handgun at home for self-protection.
Gostin, Lawrence O.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A educação como um direito fundamental de natureza social Education as a fundamental right of social nature

open access: yesEducação & Sociedade, 2007
Parece haver consenso em torno da idéia de que a educação deve ser tratada como uma prioridade por nossos governantes. Contudo, a realidade demonstra que a educação escolar de qualidade ainda é um sonho distante, sobretudo para os setores mais ...
Clarice Seixas Duarte
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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