Results 61 to 70 of about 2,004,219 (297)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
German Law JournalFundamental rights to positive state action are costly. An allocation in favor of one individual rightsholder always results in lower allocations in favor of others.
Lino Munaretto
doaj +1 more source
Bonded Labor in India: Its Incidence and Pattern [PDF]
, 2005 This Working Paper on the incidence and patterns of bonded labour in India was commissioned as an input to the ILO Director-General’s second global report on forced labor, entitled A global alliance against forced labor, prepared for the 93rd session of ...
InFocus Programme on Promoting the Declaration on Fundamental Principles and Rights at Work +2 more
core +1 more source
’The Zone of Parental Control, The ‘Gilded Cage’ And The Deprivation of a Child’s Liberty: Getting Around Article 5 [PDF]
, 2017 Purpose: This paper will specifically analyse whether parents should have the legal authority to authorise a deprivation of liberty for children with a learning disability.
. +15 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
New numbers and what they tell us about child workers in the world today
Safety and Health at Work, 2022 Michaelle De Cock, Federico Blanco
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Göttingen Journal of International Law, 2012 Traditionally, fundamental human rights have occupied an important place in labor law. The ILO constitution of 1919 focuses, for example, on the right of freedom of association.
Herman Voogsgeerd
doaj +1 more source
Fundamental Rights in the European Community Legal Order [PDF]
, 2008 The role of the courts in the protection of human rights in any legal system is a constitutionally sensitive one. The observance and protection of such rights articulate with many aspects of the exercise of governmental and legislative power.
Murray, John L.
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source