Results 71 to 80 of about 269,891 (340)

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

WAIVER OF FUNDAMENTAL RIGHTS VIA PROCEDURAL CONTRACT

open access: yesRevista Eletrônica de Direito Processual, 2019
Art. 190 of the new Brazilian Code of Civil Procedure introduced in Brazilian law the innovative institute of unenumerated procedural contracts. This work intends to examine a particular category thereof: the contract through which the agent waives her ...
Rodrigo Bley Santos
doaj   +1 more source

Pairs of Full-Rank Lattices With Parallelepiped-Shaped Common Fundamental Domains [PDF]

open access: yesarXiv, 2015
We provide a complete characterization of pairs of full-rank lattices in $\mathbb{R}^{d}$ which admit common connected fundamental domains of the type $N\left[ 0,1\right) ^{d}$ where $N$ is an invertible matrix of order $d.$ Using our characterization, we construct several pairs of lattices of the type $\left( M\mathbb{Z}^{d},\mathbb{Z}^{d}\right ...
arxiv  

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Homoafetive Union: A Question of Fundamental Rights

open access: yesRevista Brasileira de Direitos e Garantias Fundamentais, 2016
It analyzes the right to same-sex marriage. It presents different views on subjects related to the subject, to identity and to gender. It addresses fundamental rights and the constitutional principles applicable to the topic.
Renata Caroline Pereira Reis Mendes   +1 more
doaj   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Fundamental rights and private law:<br> A relationship of subordination or complementarity?

open access: yesUtrecht Law Review, 2007
Originally, private law was considered to be immune from the effect of fundamental rights, the function of which was limited to being individual defences against the vigilant eye of the state.
Olha O. Cherednychenko
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Introducing bisemistructures [PDF]

open access: yesarXiv, 2006
New fundamental mathematical structures are introduced by the triples (left semistructure,right semistructure,bisemistructure) associated with the classical mathematical structures and such that the bisemistructures,resulting from the reciprocal actions of left semistructures on right semistructures,are composed of bielements which are either diagonal ...
arxiv  

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