Results 81 to 90 of about 87,373,027 (240)

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

ESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad, Jeanne du Fay de Lavallaz, Michael J. Zhang, Thanat Chaikijurajai, Bo Ye, Prabhjot S. Nijjar, Julie A. Lahiri, Cindy M. Martin, Tamas Alexy, Markus Meyer   +9 more
wiley   +1 more source

Synthesis of β‐ and γ‐Carbolinones Through a Fe(III)‐Mediated Radical 6‐Endo‐Trig Cyclization of Indole‐Based Ugi 4‐CR Adducts

European Journal of Organic Chemistry, EarlyView.
A practical strategy for synthesizing β‐ and γ‐carbolinones from indole‐based Ugi 4‐CR adducts through an intramolecular radical cyclization using Fe(III)–H species is presented. This approach enables the efficient synthesis of spiro‐carbolinones under mild reaction conditions and demonstrates the effectiveness of secondary radicals in both cyclization
María F. Olvera‐Granados, Luis A. Polindara‐García   +1 more
wiley   +1 more source

SOR-Based numerical modeling of hybrid nanofluid flow over a rotating disk with magneto–nonlinear radiation and arrhenius activation energy considering shape factors

Scientific Reports
In this study, the effects of nonlinear thermal radiation, Arrhenius activation energy, and chemical reactions on the flow and heat transfer of a water-based hybrid nanofluid containing SWCNT- $$TiO_{2}$$ & MWCNT- $$CoFe_{2} O_{4} \,$$ nanoparticles over
Anique Ahmad, Kashif Ali, Rashid Abbas, Shahzad Ahmad, Muhammad Ramzan, Ioan-Lucian Popa   +5 more
doaj   +1 more source

Conditional Symmetries and Riemann Invariants for Hyperbolic Systems of PDEs [PDF]

, 2007
This paper contains an analysis of rank-k solutions in terms of Riemann invariants, obtained from interrelations between two concepts, that of the symmetry reduction method and of the generalized method of characteristics for first order quasilinear ...
Huard, Benoit, Grundland, A. Michel
core   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Regularity of Time-Periodic Solutions to Autonomous Semilinear Hyperbolic PDEs

, 2023
This paper concerns autonomous boundary value problems for 1D semilinear hyperbolic PDEs. For time-periodic classical solutions, which satisfy a certain non-resonance condition, we show the following: If the PDEs are continuous with respect to the space ...
Kmit, Irina, Recke, Lutz
core  

Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals

Epilepsia Open, EarlyView.
Abstract Objective To evaluate the management practices of Infantile Epileptic Spasms Syndrome (IESS) across tertiary pediatric hospitals in the United States using a survey‐based approach. Methods A 21‐question survey focused on management setting, work‐up, follow‐up and treatment was created and sent to 45 member institutions of the Pediatric ...
Akshat Katyayan, Christina Briscoe, Sonam Bhalla, Sonal Bhatia, Gozde Erdemir, Chellamani Harini, Senyene E. Hunter, John R. Mytinger, Duyu Nie, Archana Pasupuleti, Shital H. Patel, Debopam Samanta, Amanda Sandoval Karamian, Avantika Singh, Deepa Sirsi, Danielle S. Takacs, Shaun A. Hussain   +16 more
wiley   +1 more source

Automatic computation of the travelling wave solutions to nonlinear PDEs

, 2008
Various extensions of the tanh-function method and their implementations for finding explicit travelling wave solutions to nonlinear partial differential equations (PDEs) have been reported in the literature.
CPC, Mendeley
core   +1 more source

Convergence and Residual Error Analysis of Unsteady MHD Stagnation Flow Over a Cylindrical Surface With Streamline and Isotherm Visualization

Energy Science &Engineering, EarlyView.
The novelty of the current study is that the unsteady MHD Cross nanofluid model is, for the first time, coupled with the melting heat transfer at the stagnation point over a horizontally extended cylinder in a Darcy–Forchheimer porous medium. This work connects complex rheological behaviors and phase‐change phenomena in a unique way, with the only ...
Fahad Maqbul Alamrani, Ebrahem A. Algehyne, Mounirah Areshi, Muhammad Bilal, Mustafa Bayram, Jihad Younis, Anwar Saeed   +6 more
wiley   +1 more source