Results 71 to 80 of about 31,990 (181)

Addressing Small Data Challenges in Biopharmaceutical Development and Manufacturing: A Mini Review of Multi‐Fidelity Techniques

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal   +2 more
wiley   +1 more source

Advanced physics-informed neural networks for nonlinear partial differential equations: machine learning, gradient-enhanced and extended approach

open access: yesBoundary Value Problems
Nonlinear partial differential equations (NLPDEs) are fundamental in describing various physical and engineering processes. In this study, two advanced deep learning frameworks the gradient-enhanced physics-informed neural network (gPINN) (Yu et al.
Syed T. R. Rizvi   +3 more
doaj   +1 more source

Numerical and Experimental Assessment of Oxygen Distribution in a Perfusion Bioreactor to Mimic the Osteochondral Niche

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Oxygen supply is a critical parameter in 3D cell cultivation using bioreactors. Since bioreactor designs often prioritise practical constraints, understanding the oxygen supply dynamics of the media is crucial for achieving either uniform or spatially controlled oxygen delivery.
Franziska Alt   +4 more
wiley   +1 more source

Successful Revascularization of Chronic Total Occlusions in Patients With Chronic Thromboembolic Pulmonary Disease

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Chronic thromboembolic pulmonary disease (CTEPD) leads to chronic total occlusions (CTOs) of the pulmonary arteries in a minority of patients. Treatment of CTOs with balloon pulmonary angioplasty (BPA) may substantially improve patient hemodynamics but presents unique technical challenges and has previously been associated with a ...
Elliot J. Stein   +4 more
wiley   +1 more source

Discrete Fundamental Solution Preconditioning for Hyperbolic Systems of PDE

open access: yes, 2003
We present a new preconditioner for the iterative solution of linear systems of equations arising from discretizations of systems of first order partial differential equations (PDEs) on structured grids. Such systems occur in many important applications, including compressible fluid flow and electormagnetic wave propagation.
Brandén, Henrik   +2 more
openaire   +1 more source

Group analysis of differential equations and generalized functions

open access: yes, 1998
We present an extension of the methods of classical Lie group analysis of differential equations to equations involving generalized functions (in particular: distributions). A suitable framework for such a generalization is provided by Colombeau's theory
Kunzinger, Michael   +1 more
core   +2 more sources

The use of the mesh free methods (radial basis functions) in the modeling of radionuclide migration and moving boundary value problems [PDF]

open access: yes, 2007
Recently, the mesh free methods (radial basis functions-RBFs) have emerged as a novel computing method in the scientific and engineering computing community.
Runovc, Franc   +2 more
core  

Optimization of 3D‐Printed Structured Packings—Current State and Future Developments

open access: yesChemie Ingenieur Technik, EarlyView.
This paper gives an overview about structured packing development for distillation, surveying heuristic development cycles, computational fluid dynamics simulations, and additive manufacturing techniques. The emerging application of shape optimization to improve packings is emphasized, and its benefits, impact, and limitations are discussed.
Dennis Stucke   +3 more
wiley   +1 more source

Invariant Measure and Universality of the 2D Yang–Mills Langevin Dynamic

open access: yesCommunications on Pure and Applied Mathematics, EarlyView.
ABSTRACT We prove that the Yang–Mills (YM) measure for the trivial principal bundle over the two‐dimensional torus, with any connected, compact structure group, is invariant for the associated renormalised Langevin dynamic. Our argument relies on a combination of regularity structures, lattice gauge‐fixing and Bourgain's method for invariant measures ...
Ilya Chevyrev, Hao Shen
wiley   +1 more source

Implementation of the E×B and Grad‐B Drift in the EMC3 Code and Verification Using the Method of Manufactured Solutions

open access: yesContributions to Plasma Physics, EarlyView.
ABSTRACT Effective management of particle and power exhaust is essential for fusion reactor operation, requiring accurate 3D modeling of divertor physics. The EMC3 code is a well‐established Monte Carlo tool for plasma transport in stellarator edge regions, but until now lacked E×B$$ E\times B $$ and diamagnetic drifts.
Ruben De Wolf   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy