Results 221 to 230 of about 1,825,190 (283)

Establishing a Prognosis When Identifying Pathogenic Variants in Usher Syndrome/DFNB‐Related Genes: An Impossible Challenge?

open access: yesClinical Genetics, Volume 110, Issue 5, Page 639-641, November 2026.
As our results show that very few published variants could currently be considered causative of DFNB due to lack of precise clinical studies, strict and uniform criteria should be applied by authors publishing on USH/DFNB genes.
Ralyath Balogoun   +3 more
wiley   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, Volume 78, Issue 10, Page 1532-1543, October 2026.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian   +4 more
wiley   +1 more source

Monitoring Reactive Oxygen Species‐Induced Cellular Responses in Retinal Pigment Epithelium Cells Using Autofluorescence Multispectral Imaging

open access: yesAdvanced Photonics Research, Volume 7, Issue 10, October 2026.
Autofluorescence multispectral imaging enables label‐free assessment of oxidative stress in retinal pigment epithelial cells by capturing stressor‐specific metabolic signatures. Distinct autofluorescence patterns and redox changes allow classification of cellular stress states across multiple pathways.
Abhilash Goud Marupally   +9 more
wiley   +1 more source

Analysis of the Retinal and Choroidal Vasculature Using Ultrawidefield Fundus Imaging in Mild Cognitive Impairment and Normal Cognition. [PDF]

open access: yesOphthalmol Sci
Joseph S   +7 more
europepmc   +1 more source

From Molecular Targets to Advanced Delivery Systems: Aptamers for Precision Ocular Therapeutics

open access: yesAdvanced Therapeutics, Volume 9, Issue 10, October 2026.
Aptamer‐based strategies are revolutionizing ocular disease management through highly specific molecular recognition of disease specific molecular targets. This review systematically integrates therapeutic aptamer sequences, diagnostic aptasensor platforms, and targeted delivery strategies, highlighting design principles, ocular bioavailability ...
Minal Thacker   +4 more
wiley   +1 more source

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2181-2198, October 2026.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy   +16 more
wiley   +1 more source

Diagnostic Discordance in Recurrent Pregnancy Loss: Hysteroscopy Resolves Ultrasound–MRI Disagreement in Septate Uterus, but Concurrent Ovulation Induction Precludes Causal Attribution of the Reproductive Outcome

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Congenital uterine anomalies are an important and potentially treatable contributor to recurrent pregnancy loss (RPL). The septate uterus is the commonest Müllerian anomaly linked to first‐trimester loss, and its differentiation from the benign arcuate uterus is essential for management, yet imaging modalities may disagree.
Iftekhar Ahmed Sakib   +2 more
wiley   +1 more source

Advanced Primary Cervical Carcinosarcoma With Ovarian and Peritoneal Metastases in a Premenopausal Woman: A Rare Case Report From Northern Tanzania

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Cervical carcinosarcoma (CCS), also known as malignant mixed Müllerian tumor (MMMT) of the cervix, is an exceptionally rare and aggressive biphasic neoplasm composed of both epithelial and mesenchymal malignant components. Due to its rarity, optimal management strategies are not well established, particularly in low‐resource settings.
John Lugata   +11 more
wiley   +1 more source

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