Results 91 to 100 of about 454,694 (265)
Azole antifungals inhibit the cytochrome P450-dependent lanosterol 14-α-demethylase (CYP51), an essential enzyme in the ergosterol biosynthetic pathway. While azole resistance mechanisms are well established in Aspergillus fumigatus, the molecular basis ...
Ya Bin Zhou +4 more
doaj +1 more source
Paraborg: Paramedic Cyborg Insects for In Situ Emergency Drug‐Delivery
This work introduces Paraborg, a human‐supervised paramedic cyborg‐insect platform that combines controllable locomotion, onboard imaging, and an auto‐injection mechanism for in situ drug‐delivery. By demonstrating reliable navigation, target stabilization, injector launch, and multi‐insect teamwork, the study extends cyborg insects from survivor ...
H. Nhan Le +5 more
wiley +1 more source
Cremastra appendiculata is a medicinally important orchid whose seed germination depends on fungal symbionts. Here, we present the first telomere-to-telomere (T2T) genome assembly of the orchid mycorrhizal fungus Coprinellus disseminatus, comprising 15 ...
Wenyan Huo +8 more
doaj +1 more source
From Circuits to Symphonies: A Systems‐Engineering Blueprint for Multimicrobial Synthetic Biology
Engineering synthetic microbial consortia requires moving beyond intracellular genetic circuits toward coordinated multicellular design. A modular systems‐engineering framework is presented that integrates communication, temporal coordination, ecological structuring, and predictive modeling to guide application‐dependent consortium design ...
Miguel Fernández‐Niño +9 more
wiley +1 more source
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan +7 more
wiley +1 more source
The glycoside hydrolase family 3 (GH3) β-glucosidases from filamentous fungi are crucial industrial enzymes facilitating the complete degradation of lignocellulose, by converting cello-oligosaccharides and cellobiose into glucose.
Andika Sidar +5 more
doaj +1 more source
ABSTRACT This study investigates the impact of geographical indication (GI) certification on the export performance of Turkish agri‐food products by analyzing both trade volume and unit value dynamics. Drawing on monthly data from 2000 to 2024 across 22 GI‐certified products, the research employs product‐level regressions, fixed‐effects panel models ...
Ihlas Sovbetov, Muge Burcu Ozdemir
wiley +1 more source
To study the effects of dazomet, which is a soil fumigant and microbial inoculant (Trichoderma harzianum) on the bacterial and fungal diversity of continuously cropped strawberry soil, this work aimed to provide a theoretical basis for the treatment of ...
Ran Wu, Yan Li, Jian Meng, Jiangwei Han
doaj +1 more source

