Fungal Dysbiosis and Intestinal Inflammation in Children With Beta-Cell Autoimmunity [PDF]
Frontiers in Immunology, 2020 Although gut bacterial dysbiosis is recognized as a regulator of beta-cell autoimmunity, no data is available on fungal dysbiosis in the children at the risk of type 1 diabetes (T1D).
Jarno Honkanen +17 more
doaj +8 more sources
Fecal Fungal Dysbiosis in Chinese Patients With Alzheimer’s Disease [PDF]
Frontiers in Cell and Developmental Biology, 2021 Gut bacterial dysbiosis plays a vital role in the development of Alzheimer’s disease (AD). However, our understanding of alterations to the gut fungal microbiota and their correlations with host immunity in AD is still limited. Samples were obtained from
Zongxin Ling +8 more
doaj +5 more sources
Fungal dysbiosis: immunity and interactions at mucosal barriers [PDF]
Nature Reviews Immunology, 2017 (Uploaded by Plazi for the Bat Literature Project) The term dysbiosis has been used to describe disruptions of microbial communities that lead to a shift in steady-state composition that is distinct from that induced by infections. Recent work has suggested that, in addition to bacterial dysbiosis, fungal dysbiosis might contribute to the pathology of ...
Iliyan D Iliev, Irina Leonardi
exaly +5 more sources
Gut bacterial and fungal dysbiosis in tuberculosis patients [PDF]
BMC MicrobiologyBackground Recent studies have more focused on gut microbial alteration in tuberculosis (TB) patients. However, no detailed study on gut fungi modification has been reported till now.
MeiQing Han +8 more
doaj +4 more sources
Fungal Microbiota Dysbiosis and Ecological Alterations in Gastric Cancer
Frontiers in Microbiology, 2022 Changes in bacteriome composition have a strong association with gastric cancer (GC). However, the relationship between stomach fungal microbiota composition and human host immune factors remains largely unknown. With high-throughput internal transcribed
Ping Yang +11 more
doaj +3 more sources
Therapeutic potential of an intestinotrophic hormone, glucagon-like peptide 2, for treatment of type 2 short bowel syndrome rats with intestinal bacterial and fungal dysbiosis [PDF]
BMC Infectious Diseases, 2021 Background Previous studies showed that type 2 short bowel syndrome (SBS) rats were accompanied by severe intestinal bacterial dysbiosis. Limited data are available for intestinal fungal dysbiosis.
Xiuting Hu +6 more
doaj +2 more sources
Tryptophan metabolism and bacterial commensals prevent fungal dysbiosis in Arabidopsis roots. [PDF]
Proc Natl Acad Sci U S A, 2021 Significance Understanding how host–microbe homeostasis is controlled and maintained in plant roots is key to enhance plant productivity. However, the factors that contribute to the maintenance of this equilibrium between plant roots and their multikingdom microbial communities remain largely unknown.
Wolinska KW +10 more
europepmc +6 more sources
Proton pump inhibitors induced fungal dysbiosis in patients with gastroesophageal reflux disease. [PDF]
Front Cell Infect Microbiol, 2023 Gut mycobiota inhabits human gastrointestinal lumen and plays a role in human health and disease. We investigated the influence of proton pump inhibitors (PPIs) on gastric mucosal and fecal mycobiota in patients with gastroesophageal reflux diseases (GERD) by using Internal Transcribed Spacer 1 sequencing.
Shi Y +6 more
europepmc +4 more sources
Immunological Consequences of Intestinal Fungal Dysbiosis. [PDF]
Cell Host Microbe, 2016 Compared to bacteria, the role of fungi within the intestinal microbiota is poorly understood. In this study we investigated whether the presence of a "healthy" fungal community in the gut is important for modulating immune function. Prolonged oral treatment of mice with antifungal drugs resulted in increased disease severity in acute and chronic ...
Wheeler ML +12 more
europepmc +6 more sources
Fungal dysbiosis facilitates inflammatory bowel disease by enhancing CD4+ T cell glutaminolysis. [PDF]
Front Cell Infect Microbiol, 2023 The fungal microbiota is an important component of the complex multikingdom microbial community colonizing the mammalian gastrointestinal tract and has an important role in immune regulation. However, how fungi regulate inflammatory bowel disease (IBD) is poorly understood.
Yu M +8 more
europepmc +4 more sources