Results 41 to 50 of about 11,622 (186)

Altered Gut Microbiota in Patients With Peutz–Jeghers Syndrome

Frontiers in Microbiology, 2022
BackgroundPeutz–Jeghers syndrome (PJS) is a rare genetic disorder characterized by the development of pigmented spots and gastrointestinal polyps and increased susceptibility to cancers.
Sui Wang, Sui Wang, Gang Huang, Gang Huang, Jue-Xin Wang, Jue-Xin Wang, Lin Tian, Lin Tian, Xiu-Li Zuo, Xiu-Li Zuo, Yan-Qing Li, Yan-Qing Li, Yan-Bo Yu, Yan-Bo Yu   +13 more
doaj   +1 more source

Microbiome dysbiosis and alcoholic liver disease

Liver Research, 2019
Microbiome dysbiosis is strongly associated with alcoholic liver disease (ALD). Recent studies on comprehensive analyses of microbiome compositional and functional changes have begun to uncover the mechanistic relation between microbiome and the ...
Fengyuan Li, Craig J. McClain, Wenke Feng   +2 more
doaj   +1 more source

Gut Micro- and Mycobiota in Preeclampsia: Bacterial Composition Differences Suggest Role in Pathophysiology

Biomolecules, 2023
Preeclampsia is a severe pregnancy-related inflammatory disease without an effective treatment. The pathophysiology remains partly unknown. However, an increased inflammatory response and oxidative stress are part of the maternal systemic reaction ...
Sofie Meijer, Elena Pasquinelli, Sonia Renzi, Shahram Lavasani, Mehrnaz Nouri, Lena Erlandsson, Duccio Cavalieri, Stefan R. Hansson   +7 more
doaj   +1 more source

A review on association of fungi with the development and progression of carcinogenesis in the human body

Current Research in Microbial Sciences, 2022
The role and impact of commensal and pathogenic fungi in different parts of the human body are being increasingly appreciated, unveiling the importance of such microorganisms in human health.
Marie Andrea Laetitia Huët, Chuen Zhang Lee, Sadequr Rahman   +2 more
doaj   +1 more source

Gut Mycobiome and Asthma

Journal of Fungi
This review explores the ‘gut–lung axis’ in asthma with a focus on commensal fungal organisms. We explore how changes to the intestinal commensal fungal community composition alter lung immune function.
Amjad N. Kanj, Joseph H. Skalski
doaj   +1 more source

Exploring the gut mycobiome: differential composition and clinical associations in hypertension, chronic kidney disease, and their comorbidity

Frontiers in Immunology, 2023
BackgroundHypertension (HTN) and chronic kidney disease (CKD) pose significant global health challenges and often coexist, amplifying cardiovascular risks.
Juan Qiu, Longyou Zhao, Yiwen Cheng, Yiwen Cheng, Qiaoxia Chen, Yiran Xu, Yingfeng Lu, Jie Gao, Wenhui Lei, Wenhui Lei, Chengmin Yan, Zongxin Ling, Zongxin Ling, Shaochang Wu   +13 more
doaj   +1 more source

Fungal Gut Microbiota Dysbiosis and Its Role in Colorectal, Oral, and Pancreatic Carcinogenesis [PDF]

Cancers, 2020
The association between bacterial as well as viral gut microbiota imbalance and carcinogenesis has been intensively analysed in many studies; nevertheless, the role of fungal gut microbiota (mycobiota) in colorectal, oral, and pancreatic cancer development is relatively new and undiscovered field due to low abundance of intestinal fungi as well as lack
Karolina Kaźmierczak-Siedlecka, Aleš Dvořák, Marcin Folwarski, Agnieszka Daca, Katarzyna Przewłócka, Wojciech Makarewicz   +5 more
openaire   +2 more sources

Association between fungal dysbiosis in the first 1 000 days of life and childhood diseases – a review of research progress

Zhongguo gonggong weisheng
Bacteria, as the major component of the human microbiome, have been shown to play important physiological roles in human health and disease development.
Xiaoyan ZHANG, Xiaochuan WANG, Borui LIU, Jing YANG, Xiaoyu GAO, Jiajin HU   +5 more
doaj   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Decoding the role of gut mycobiota in immune regulation and disease

Virulence
The gut mycobiota, a minor but influential component of the microbiota, is increasingly recognized for its role in shaping host immunity and influencing health.
Tiantian Zhang, Feifan Guo, Cihan Zhang, Youqun Xiang   +3 more
doaj   +1 more source