Results 61 to 70 of about 13,270 (230)
Advanced Science, EarlyView.We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai +8 more
wiley +1 more source
Table_3_Fungal Dysbiosis and Intestinal Inflammation in Children With Beta-Cell Autoimmunity.DOCX
, 2020 Although gut bacterial dysbiosis is recognized as a regulator of beta-cell autoimmunity, no data is available on fungal dysbiosis in the children at the risk of type 1 diabetes (T1D).
Daniel Muthas (2143111) +14 more
core +1 more source
Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity
Advanced Science, EarlyView.Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai +7 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat +5 more
wiley +1 more source
mSphere, 2018 Clostridium difficile infection (CDI) is the most common nosocomial infection in the United States, being associated with high recurrence and persistence rates.
Regina Lamendella +10 more
doaj +1 more source
Image_2_Fungal Dysbiosis and Intestinal Inflammation in Children With Beta-Cell Autoimmunity.TIF
, 2020 Although gut bacterial dysbiosis is recognized as a regulator of beta-cell autoimmunity, no data is available on fungal dysbiosis in the children at the risk of type 1 diabetes (T1D).
Daniel Muthas (2143111) +14 more
core +1 more source
Animal Models and Experimental Medicine, EarlyView.Gut microbiota from patients with type 2 diabetes induced early diabetes‐like phenotypes in germ‐free mice, including progressive glucose intolerance and mild renal injury. Longitudinal profiling revealed persistent dysbiosis preceding stable metabolic dysfunction, with coordinated fecal and plasma metabolite alterations and a prominent L‐Dopa ...
Jianghao Feng +6 more
wiley +1 more source
Alterations in the gut bacterial microbiome in fungal Keratitis patients. [PDF]
PLoS ONE, 2018 Dysbiosis in the gut microbiome has been implicated in several diseases including auto-immune diseases, inflammatory diseases, cancers and mental disorders.
Sama Kalyana Chakravarthy +9 more
doaj +1 more source
Dysbiosis of Gut Fungal Microbiota is Associated With Mucosal Inflammation in Crohn’s Disease [PDF]
Journal of Clinical Gastroenterology, 2014 We aim to characterize the fungal microbiota in the intestinal mucosa and feces in patients with Crohn's disease (CD).Fungi represent a diverse microbial community in the human intestine and might play a role in the pathogenesis of CD; however, little is known about the structure and composition of the fungal microbiota especially adhering to the ...
Li, Qiurong +5 more
openaire +2 more sources
Image_5_Fungal Dysbiosis and Intestinal Inflammation in Children With Beta-Cell Autoimmunity.tif
, 2020 Although gut bacterial dysbiosis is recognized as a regulator of beta-cell autoimmunity, no data is available on fungal dysbiosis in the children at the risk of type 1 diabetes (T1D).
Daniel Muthas (2143111) +14 more
core +1 more source