Results 11 to 20 of about 255,611 (316)
Ca2+ Signalling Differentially Regulates Germ-Tube Formation and Cell Fusion in Fusarium oxysporum
Journal of Fungi, 2022 Fusarium oxysporum is an important plant pathogen and an emerging opportunistic human pathogen. Germination of conidial spores and their fusion via conidial anastomosis tubes (CATs) are significant events during colony establishment in culture and on ...
Smija M. Kurian +2 more
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Pathogenicity and virulence of Aspergillus fumigatus
Virulence, 2023 Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major cause of morbidity and mortality globally. Compromised lung defences arising from immunosuppression, chronic respiratory conditions or more recently, concomitant viral or
Kayleigh Earle +7 more
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Journal of Fungi, 2021 The precise characterization of the mechanisms modulating Aspergillus fumigatus survival within airway epithelial cells has been impaired by the lack of live-cell imaging technologies and user-friendly quantification approaches. Here we described the use
Nagwa Ben-Ghazzi +7 more
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The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
Nature Communications, 2020 Resistance to primary treatments of invasive aspergillosis is growing. Here, the authors generate a knockout library for 484 transcription factors in Aspergillus fumigatus, and show that loss of the NCT complex leads to cross-resistance to all primary ...
Takanori Furukawa +22 more
doaj +1 more source
MycoKeys, 2018 During the course of a study on the functional biodiversity of the mycobiota inhabiting rainforests in Thailand, a fungal strain was isolated from a plant sample and shown to represent an undescribed species, as inferred from a combination of ...
Zeljka Rupcic +5 more
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Lung colonization by Aspergillus fumigatus is controlled by ZNF77
Nature Communications, 2018 Aspergillus fumigatus regularly colonises the lungs but in the context of respiratory disease can be associated with increased pathology. Here the authors show mutations in ZNF77 result in altered bronchial epithelial characteristics and enhanced fungal ...
Sara Gago +6 more
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Poorly controlled asthma – Easy wins and future prospects for addressing fungal allergy
Allergology International, 2023 Poorly controlled asthma is especially common in low resource countries. Aside from lack of access to, or poor technique with, inhaled beta-2 agonists and corticosteroids, the most problematic forms of asthma are frequently associated with both fungal ...
David W. Denning, Lorraine T. Pfavayi
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A protein–protein interaction inhibitor arrests the cell cycle in Aspergillus fumigatus
mBioInvasive infections caused by Aspergillus fumigatus have high mortality rates, even when treated with the first-line agent voriconazole. The global emergence of azole resistance further increases treatment failure, underscoring the urgent need for ...
I. S. R. Storer +4 more
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Pulmonary fungal infections [PDF]
Respirology, 2012 ABSTRACTThis review details some of the advances that have been made in the recent decade in the diagnosis, treatment and epidemiology of pulmonary fungal infections. These advances have occurred because of increasing knowledge regarding the fungal genome, better understanding of the structures of the fungal cell wall and cell membrane and the use of ...
Smith, Jeannina A., Kauffman, Carol A.
openaire +3 more sources
Estimated burden of fungal infections in Kenya
Journal of Infection in Developing Countries, 2016 Introduction: Kenya is a developing country with a high rate of tuberculosis (TB) and a moderate HIV infection burden. No estimate of the burden of fungal diseases in Kenya is published.
John Abuga Guto +2 more
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